| Factor analysis of the clinical characteristics of primary Sjogren syndrome. | |
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MedLine Citation:
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PMID: 20802365 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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PURPOSE: The purpose of this study was to use factor analysis to analyze 90 clinical characteristics of a cohort of 231 patients with primary Sjogren syndrome (pSS). METHODS: The records of all patients seen at the University Health Network Sjogren Syndrome Clinic from October 1992 to July 2006 were reviewed and documented. Those diagnosed as pSS by the American European Consensus Criteria of 2002 were included. The 90 clinical variables, including health history, blood analysis, symptoms of dry eye and dry mouth, salivary flow and biopsy, tear flow and staining, were analyzed by factor analysis. RESULTS: Two hundred thirty-one patients with pSS charts were reviewed, and 90 variables were recorded. Factor analysis resulted in three factors: factor 1: ocular surface staining, factor 2: antimicrosomal antibodies and antithyroid antibodies, and factor 3: serum anti-Ro and anti-La. CONCLUSIONS: Ocular surface staining accounted for the greatest variance in this population of patients with pSS. |
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Authors:
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Barbara Caffery; Trefford Simpson; Sunny Wang; Denis Bailey; John McComb; John Rutka; Allan Slomovic; Arthur Bookman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Optometry and vision science : official publication of the American Academy of Optometry Volume: 87 ISSN: 1538-9235 ISO Abbreviation: Optom Vis Sci Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8904931 Medline TA: Optom Vis Sci Country: United States |
Other Details:
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Languages: eng Pagination: 742-50 Citation Subset: IM |
Affiliation:
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School of Optometry, University of Waterloo, Waterloo, Ontario, Canada. barbaracafferyeyes@yahoo.ca |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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