Document Detail


Factitious pheochromocytoma: novel mimickry by Valsalva maneuver and clues to diagnosis.
MedLine Citation:
PMID:  7662252     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Factitious pheochromocytoma usually occurs in patients surreptitiously ingesting adrenergic medications. We encountered a case of factitious pheochromocytoma where in the subject mimicked hemodynamic (profound hypertension) and biochemical (plasma catecholamine elevation) manifestations of the illness by consciously altering autonomic function with Valsalva maneuver. Clues to this presentation included visible performance of Valsalva maneuver, marked disparity between blood pressures recorded in the presence and absence of the subject's knowledge, normal urinary catecholamine and metabolite excretion, and normal plasma chromogranin A. We reproduced, in part, the hemodynamic and biochemical manifestations of this presentation with Valsalva maneuver in healthy subjects.
Authors:
M T Kailasam; R J Parmer; R A Stone; S Shankel; B P Kennedy; M G Ziegler; D T O'Connor
Publication Detail:
Type:  Case Reports; Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of hypertension     Volume:  8     ISSN:  0895-7061     ISO Abbreviation:  Am. J. Hypertens.     Publication Date:  1995 Jun 
Date Detail:
Created Date:  1995-10-11     Completed Date:  1995-10-11     Revised Date:  2009-02-24    
Medline Journal Info:
Nlm Unique ID:  8803676     Medline TA:  Am J Hypertens     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  651-5     Citation Subset:  IM    
Affiliation:
Department of Medicine, University of California, San Diego 92161, USA.
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MeSH Terms
Descriptor/Qualifier:
Adrenal Gland Neoplasms / diagnosis*,  physiopathology
Adult
Blood Pressure / physiology
Catecholamines / blood
Chromogranin A
Chromogranins / blood
Diagnosis, Differential
Factitious Disorders / diagnosis*,  physiopathology
Female
Humans
Male
Pheochromocytoma / diagnosis*,  physiopathology
Substance-Related Disorders / diagnosis
Valsalva Maneuver*
Chemical
Reg. No./Substance:
0/Catecholamines; 0/Chromogranin A; 0/Chromogranins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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