| Facilitation of laryngeal mask airway insertion: effects of remifentanil administered before induction with target-controlled propofol infusion. | |
MedLine Citation:
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PMID: 11531680 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Eighty-six adult day-case patients were recruited into a prospective, randomised study and allocated to one of two groups. Patients received either intravenous remifentanil 0.3 microg.kg(-1) or an equivalent volume of sodium chloride 0.9% followed by induction of anaesthesia with propofol target-controlled infusion until the effect (brain) site calculated concentration was 2 microg.ml(-1). Jaw opening and ease of laryngeal mask insertion were assessed immediately after mask insertion. A higher incidence of failure of induction of anaesthesia was observed in the control group compared with the remifentanil group [15 (35%) vs. 3 (7%); p < 0.01] and addition of remifentanil significantly increased the ease and success of laryngeal mask insertion, with grade 1 (no coughing/gagging) conditions observed in 29 (68%) of the remifentanil group and 21 (49%) of the control group (p < 0.01). The doses of remifentanil and propofol used were not associated with any significant cardiorespiratory instability. In conclusion, when combined with propofol target-controlled infusion, remifentanil 0.3 microg.kg(-1) facilitates laryngeal mask insertion with minimal adverse haemodynamic changes. |
Authors:
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K Grewal; G Samsoon |
Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Anaesthesia Volume: 56 ISSN: 0003-2409 ISO Abbreviation: Anaesthesia Publication Date: 2001 Sep |
Date Detail:
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Created Date: 2001-09-04 Completed Date: 2001-09-20 Revised Date: 2009-11-03 |
Medline Journal Info:
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Nlm Unique ID: 0370524 Medline TA: Anaesthesia Country: England |
Other Details:
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Languages: eng Pagination: 897-901 Citation Subset: AIM; IM |
Affiliation:
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Department of Anaesthetics, St George's Hospital, Blackshaw Road, London SW17 0QT, UK. kirangrewal67@hotmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Ambulatory Surgical Procedures Analgesics, Opioid* / pharmacology Anesthetics, Intravenous* Female Hemodynamics / drug effects Humans Intubation, Intratracheal / methods Laryngeal Masks* Male Middle Aged Oxygen / blood Piperidines* / pharmacology Propofol* Prospective Studies Respiratory Mechanics / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Analgesics, Opioid; 0/Anesthetics, Intravenous; 0/Piperidines; 132875-61-7/remifentanil; 2078-54-8/Propofol; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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