Document Detail

Facilitation of laryngeal mask airway insertion: effects of remifentanil administered before induction with target-controlled propofol infusion.
MedLine Citation:
PMID:  11531680     Owner:  NLM     Status:  MEDLINE    
Eighty-six adult day-case patients were recruited into a prospective, randomised study and allocated to one of two groups. Patients received either intravenous remifentanil 0.3 or an equivalent volume of sodium chloride 0.9% followed by induction of anaesthesia with propofol target-controlled infusion until the effect (brain) site calculated concentration was 2 Jaw opening and ease of laryngeal mask insertion were assessed immediately after mask insertion. A higher incidence of failure of induction of anaesthesia was observed in the control group compared with the remifentanil group [15 (35%) vs. 3 (7%); p < 0.01] and addition of remifentanil significantly increased the ease and success of laryngeal mask insertion, with grade 1 (no coughing/gagging) conditions observed in 29 (68%) of the remifentanil group and 21 (49%) of the control group (p < 0.01). The doses of remifentanil and propofol used were not associated with any significant cardiorespiratory instability. In conclusion, when combined with propofol target-controlled infusion, remifentanil 0.3 facilitates laryngeal mask insertion with minimal adverse haemodynamic changes.
K Grewal; G Samsoon
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Anaesthesia     Volume:  56     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-09-04     Completed Date:  2001-09-20     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  England    
Other Details:
Languages:  eng     Pagination:  897-901     Citation Subset:  AIM; IM    
Department of Anaesthetics, St George's Hospital, Blackshaw Road, London SW17 0QT, UK.
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MeSH Terms
Ambulatory Surgical Procedures
Analgesics, Opioid* / pharmacology
Anesthetics, Intravenous*
Hemodynamics / drug effects
Intubation, Intratracheal / methods
Laryngeal Masks*
Middle Aged
Oxygen / blood
Piperidines* / pharmacology
Prospective Studies
Respiratory Mechanics / drug effects
Reg. No./Substance:
0/Analgesics, Opioid; 0/Anesthetics, Intravenous; 0/Piperidines; 132875-61-7/remifentanil; 2078-54-8/Propofol; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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