| Facile formation of N-acyl-oxazolidinone derivatives using acid fluorides. | |
| | |
MedLine Citation:
|
PMID: 20707372 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A mild method is presented for the formation of N-acylated oxazolidinones that employs acid fluorides and mild bases, such as (i)Pr(2)NEt and NEt(3). Optimized reaction conditions for two types of substrates have been developed utilizing either the oxazolidinone itself or the corresponding in situ generated O-silyloxazolidinones resulting in the formation of the desired N-acylated products in high yields of up to 98%. |
| | |
Authors:
|
Corinna S Schindler; Patrik M Forster; Erick M Carreira |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Organic letters Volume: 12 ISSN: 1523-7052 ISO Abbreviation: Org. Lett. Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-09-10 Completed Date: 2010-12-21 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100890393 Medline TA: Org Lett Country: United States |
Other Details:
|
Languages: eng Pagination: 4102-5 Citation Subset: IM |
Affiliation:
|
Laboratorium für Organische Chemie, ETH Zürich, Wolfgang-Pauli-Strasse 10, 8093 Zürich, Switzerland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acids
/
chemistry* Acylation Fluorides / chemistry* Molecular Structure Oxazolidinones / chemical synthesis* |
| Chemical | |
Reg. No./Substance:
|
0/Acids; 0/Fluorides; 0/Oxazolidinones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Surfactant-mediated ion exchange and charge reversal at ionic liquid interfaces.
Next Document: Effects of nonionic surfactant addition on populations of polycyclic aromatic hydrocarbon-degrading ...