| Fabrication of a novel impedance cell sensor based on the polystyrene/polyaniline/Au nanocomposite. | |
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MedLine Citation:
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PMID: 19782222 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Gold nanoparticles (AuNPs) were assembled on the surface of polystyrene (PS) and polyaniline (PANI) core-shell nanocomposite (PS@PANI) for the immobilization of HL-60 leukemia cells to fabricate a cell electrochemical sensor. The immobilized cells exhibited irreversible voltammetric response and increased the electron transfer resistance with a good correlation to the logarithmic value of concentration ranging from 1.6 x 10(3) to 1.6 x 10(8) cells mL(-1) with a limit of detection of 7.3 x 10(2) cells mL(-1) at 10 sigma. This biosensor was simple, low cost and disposable, which implied that the PS@PANI/Au composites can regard as the potential applications for clinical applications. |
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Authors:
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Miaomiao Gu; Jingjing Zhang; Ye Li; Liping Jiang; Jun-Jie Zhu |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-07-04 |
Journal Detail:
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Title: Talanta Volume: 80 ISSN: 1873-3573 ISO Abbreviation: Talanta Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-09-28 Completed Date: 2010-01-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2984816R Medline TA: Talanta Country: England |
Other Details:
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Languages: eng Pagination: 246-9 Citation Subset: IM |
Affiliation:
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Key Lab of Analytical Chemistry for Life Science (MOE), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, PR China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aniline Compounds
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chemistry* Biosensing Techniques / instrumentation, methods* Cells, Immobilized Electric Impedance Electrochemistry Electrodes Gold / chemistry* HL-60 Cells Humans Microscopy, Electron, Scanning Microscopy, Electron, Transmission Nanocomposites / chemistry*, ultrastructure Polystyrenes / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Aniline Compounds; 0/Polystyrenes; 0/polyaniline; 7440-57-5/Gold |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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