Document Detail

Fabrication and characterization of porous Ti-7.5Mo alloy scaffolds for biomedical applications.
MedLine Citation:
PMID:  23314686     Owner:  NLM     Status:  Publisher    
Porous titanium and titanium alloys are promising scaffolds for bone tissue engineering, since they have the potential to provide new bone tissue ingrowth abilities and low elastic modulus to match that of natural bone. In the present study, porous Ti-7.5Mo alloy scaffolds with various porosities from 30 to 75 % were successfully prepared through a space-holder sintering method. The yield strength and elastic modulus of a Ti-7.5Mo scaffold with a porosity of 50 % are 127 MPa and 4.2 GPa, respectively, being relatively comparable to the reported mechanical properties of natural bone. In addition, the porous Ti-7.5Mo alloy exhibited improved apatite-forming abilities after pretreatment (with NaOH or NaOH + water) and subsequent immersion in simulated body fluid (SBF) at 37 °C. After soaking in an SBF solution for 21 days, a dense apatite layer covered the inner and outer surfaces of the pretreated porous Ti-7.5Mo substrates, thereby providing favorable bioactive conditions for bone bonding and growth. The preliminary cell culturing result revealed that the porous Ti-7.5Mo alloy supported cell attachment.
Hsueh-Chuan Hsu; Shih-Kuang Hsu; Hsi-Kai Tsou; Shih-Ching Wu; Tsung-Hsuan Lai; Wen-Fu Ho
Related Documents :
24591126 - A novel osteogenic oxysterol compound for therapeutic development to promote bone growt...
23814566 - Histologic and histomorphometric evaluation of the effect of lactoferrin combined with ...
23416846 - In silico investigations of potential anabolic treatments in multiple myeloma-induced b...
23953506 - Bmp-2 induced early bone formation in spine fusion using rat ovariectomy osteoporosis m...
7671516 - External fixation of pediatric femoral fractures.
12172956 - Analysis of limb alignment in the pathogenesis of osteoarthritis: a comparison of saudi...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-13
Journal Detail:
Title:  Journal of materials science. Materials in medicine     Volume:  -     ISSN:  1573-4838     ISO Abbreviation:  J Mater Sci Mater Med     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9013087     Medline TA:  J Mater Sci Mater Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Dental Technology and Materials Science, Central Taiwan University of Science and Technology, Taichung, Taiwan, ROC.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Gastrointestinal response and endotoxemia during intense exercise in hot and cool environments.
Next Document:  Impact of managed care health insurance system for indigent patients with rheumatoid arthritis in Pu...