Document Detail


Fabrication and characterization of chitosan-poly(acrylic acid) magnetic nanospheres.
MedLine Citation:
PMID:  19441507     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Iron oxide nanoparticles modified with meso-2,3-dimercaptosuccinic acid (DMSA), were encapsulated with a natural polymer with abundant primary amino groups, chitosan (CS), to improve their biocompatibility. Characterization was performed using Fourier transform infrared spectroscopy, thermogravimetirc analysis, transmission electron microscope analyses, vibrating sample magnetometer, zeta potential analyzer. It was found that highly ordered spherical aggregates with a mean diameter of 98 nm are obtained. The formation of aggregates depended on cross-linking of acrylic acid (AA) monomers and CS. These biodegradable CS-PAA polymer magnetic nanospheres might be useful for various biomedical applications.
Authors:
Yuqing Ge; Song Zhang; Shiying He; Yu Zhang; Ning Gu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of nanoscience and nanotechnology     Volume:  9     ISSN:  1533-4880     ISO Abbreviation:  J Nanosci Nanotechnol     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-05-15     Completed Date:  2009-06-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101088195     Medline TA:  J Nanosci Nanotechnol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1287-90     Citation Subset:  -    
Affiliation:
Jiangsu Laboratory for Biomaterials and Devices, State Key Laboratory of Bioelectronics, Department of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, P. R. China.
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