| Fabrication of hollow poly(lactic acid) microcapsules from microbubble templates. | |
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MedLine Citation:
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PMID: 19845373 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hollow microcapsules are expected to be integral components of drug delivery systems in medical and pharmaceutical applications. Among the methods studied, the bubble template method (Makuta et al. Mater. Lett. 2009, 63, 703-705) should easily fabricate uniform hollow microcapsules covered with biodegradable polymers. In this study, we clarified the two conditions required to fabricate uniform hollow microcapsules using the bubble template method: the stability of uniformly sized microbubbles in a liquid droplet and the release of hollow microcapsules from the droplet. Furthermore, our experiments evaluated the radius distributions of template microbubbles and fabricated hollow poly(lactic acid) microcapsules. |
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Authors:
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Hirofumi Daiguji; Shingo Takada; Jay J Molino Cornejo; Fumio Takemura |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The journal of physical chemistry. B Volume: 113 ISSN: 1520-5207 ISO Abbreviation: J Phys Chem B Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-11-05 Completed Date: 2010-01-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101157530 Medline TA: J Phys Chem B Country: United States |
Other Details:
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Languages: eng Pagination: 15002-9 Citation Subset: IM |
Affiliation:
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Institute of Environmental Studies, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8563, Japan. daiguji@k.u-tokyo.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Capsules
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chemistry* Drug Carriers / chemistry Lactic Acid* Particle Size Polymers* |
| Chemical | |
Reg. No./Substance:
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0/Capsules; 0/Drug Carriers; 0/Polymers; 26100-51-6/poly(lactic acid); 50-21-5/Lactic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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