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Fabric-Based Exocervical and Endocervical Biopsy in Comparison With Punch Biopsy and Sharp Curettage.
MedLine Citation:
PMID:  22371040     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVES: Fabric-based endocervical and exocervical biopsy tools were compared with exocervical punch biopsy and sharp endocervical curettage. We compared the level of pain reported by the patient and the amount of bleeding rated by the physician relative to the type of biopsy used. MATERIALS AND METHODS: This was a 2-center institutional review board-approved study of patients undergoing colposcopy. One center randomized patients to undergo either conventional (punch biopsy, sharp endocervical curettage) or fabric-based biopsy of the endocervix and exocervix, and a second center enrolled nonrandomized controls. The patient and physician subjectively rated bleeding (exocervical) and pain (endocervical and exocervical) from the biopsy procedure(s), which were compared using the nonparametric Wilcoxon test. RESULTS: Exocervical and endocervical biopsies from 55 patients were compared. Fabric-based biopsies were abundant full-thickness curettage and showed statistically significant less pain and bleeding than the conventional biopsy methods (p < .0001). CONCLUSIONS: Fabric-based biopsies are significantly less traumatic than conventional biopsies. The benefits of a less-invasive biopsy could increase the willingness to perform multiple biopsies, increase disease detection, and improve patient satisfaction, which could impact future gynecologic health-seeking behavior and compliance with colposcopy recall.
Authors:
Marc Winter; Ramon M Cestero; Andrew Burg; Juan C Felix; Catherine Han; Ann Marie Raffo; Steven Vasilev
Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Journal of lower genital tract disease     Volume:  16     ISSN:  1526-0976     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-2-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9704963     Medline TA:  J Low Genit Tract Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  80-87     Citation Subset:  -    
Affiliation:
1Department of Obstetrics and Gynecology, Orange Coast Women's Medical Group, Laguna Hills; 2Department of Obstetrics and Gynecology, University of California, Irvine School of Medicine, Irvine; 3Department of Obstetrics and Gynecology, Arrowhead Regional Medical Center, Colton; 4Department of Gynecological Pathology, St. Mary Medical Center, Long Beach; 5Department of Gynecological Pathology, University of Southern California Women's Hospital, Los Angeles; and 6Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA.
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