Document Detail


FTO and obesity: the missing link.
MedLine Citation:
PMID:  21195343     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Genome-wide association studies revealed that variants within FTO (fat-mass- and obesity-associated) are strongly associated with obesity susceptibility. A recent study in Nature Genetics (Church et al., 2010) demonstrates that mice overexpressing fto exhibit a dose-dependent increase in body weight, confirming a role for FTO in the development of obesity.
Authors:
I Sadaf Farooqi
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Cell metabolism     Volume:  13     ISSN:  1932-7420     ISO Abbreviation:  Cell Metab.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101233170     Medline TA:  Cell Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  7-8     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 2QQ, UK. isf20@cam.ac.uk
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Comment On:
Nat Genet. 2010 Dec;42(12):1086-92   [PMID:  21076408 ]

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