Document Detail


FTO and obesity: a problem for a billion people.
MedLine Citation:
PMID:  22248259     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
It is an inescapable fact that obesity results from consuming more energy than you burn. The interesting question, however, is why some people eat more than others? Recent genetic analyses have revealed that variations in the fat mass and obesity-associated (FTO) gene are robustly associated with obesity and increased food intake. This association is replicable across different age groups in multiple populations and attention is now turned to studying the complex biology of FTO.
Authors:
Giles S H Yeo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neuroendocrinology     Volume:  24     ISSN:  1365-2826     ISO Abbreviation:  J. Neuroendocrinol.     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-17     Completed Date:  2012-05-17     Revised Date:  2014-02-20    
Medline Journal Info:
Nlm Unique ID:  8913461     Medline TA:  J Neuroendocrinol     Country:  England    
Other Details:
Languages:  eng     Pagination:  393-4     Citation Subset:  IM    
Copyright Information:
© 2011 The Author. Journal of Neuroendocrinology © 2011 Blackwell Publishing Ltd.
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MeSH Terms
Descriptor/Qualifier:
Animals
Appetite Regulation / genetics,  physiology
Body Mass Index
Brain / metabolism,  physiology
Energy Intake / genetics,  physiology
Genetic Predisposition to Disease
Humans
Mice
Models, Biological
Motor Activity / physiology
Obesity / epidemiology*,  genetics*
Overweight / epidemiology,  genetics
Prevalence
Proteins / genetics,  metabolism,  physiology*
Grant Support
ID/Acronym/Agency:
G0600717//Medical Research Council
Chemical
Reg. No./Substance:
0/FTO protein, human; 0/Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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