| FSH time-concentration profiles before and after administration of 0.25 mg cetrorelix in the gnRH-antagonist multiple-dose protocol for ovarian hyperstimulation. | |
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MedLine Citation:
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PMID: 15526986 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To determine FSH concentration behavior before and after cetrorelix 0.25 mg administration in the GnRH-antagonist multiple-dose protocol on day 6 of ovarian stimulation with 150-300 IU daily recombinant FSH. METHODS: Blood samples for FSH measurements were drawn from seven women every 15 min from 8 h prior to the first cetrorelix administration in the GnRH-antagonist multiple-dose protocol until 15-32 h thereafter. RESULTS: No significant change of FSH concentration was observed. CONCLUSIONS: This observation indicates that no rationale exists of increasing the daily FSH dosage concomitantly to the GnRH-antagonist administration to compensate for a drop of endogenous FSH. |
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Authors:
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G Griesinger; D Finas; A Alisch; K Roiha; A Schultze-Mosgau; A K Schröder; K Dafopoulos; K Diedrich; R Felberbaum |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of assisted reproduction and genetics Volume: 21 ISSN: 1058-0468 ISO Abbreviation: J. Assist. Reprod. Genet. Publication Date: 2004 Jul |
Date Detail:
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Created Date: 2004-11-05 Completed Date: 2004-12-09 Revised Date: 2013-05-29 |
Medline Journal Info:
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Nlm Unique ID: 9206495 Medline TA: J Assist Reprod Genet Country: United States |
Other Details:
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Languages: eng Pagination: 279-82 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Medical University of Schleswig-Holstein, Campus Luebeck, 23538 Luebeck, Germany. georg.griesinger@frauenklinik.uni-luebeck.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers
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blood Drug Administration Schedule Female Follicle Stimulating Hormone / blood* Gonadotropin-Releasing Hormone / administration & dosage, analogs & derivatives*, therapeutic use* Hormone Antagonists / therapeutic use Humans Ovulation Induction / methods* |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Hormone Antagonists; 33515-09-2/Gonadotropin-Releasing Hormone; 9002-68-0/Follicle Stimulating Hormone; OON1HFZ4BA/cetrorelix |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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