| FFA and insulin response dissociation to gradual short-term food restriction in exercising rats. | |
| | |
MedLine Citation:
|
PMID: 3312047 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The present study examines the metabolic and hormonal responses of progressive short-term food restriction in rats at rest and during exercise. The night prior to the experiment, previously cannulated rats were assigned to one of three groups: (A) normal diet, (B) 50% food restriction, and (C) 75% food restriction. They were then run continuously for 50 min at 26 m.min-1, 0% grade. Resting liver glycogen levels were decreased in groups B and C (50% and 92%) while B-hydroxybutyrate values were increased in group C only. A similar group main effect (resting and exercise values) of a significant (P less than 0.05) increase in free fatty acid concentrations was found in groups B and C as compared to group A, while a decrease in insulin (P less than 0.01) and glucose (P less than 0.05) concentrations was observed in group C only. Norepinephrine and epinephrine concentrations were increased similarly in all three groups following exercise. Resting muscle glycogen levels were progressively reduced following food restrictions. These results indicate that (1) food deprivation at rest and during exercise first affects free fatty acid concentrations and thereafter the insulin response, (2) prolonged exercise following food restrictions increases the metabolic adaptative state of the resting organism. These findings are in disagreement with a sole action of pre-exercise insulin as a determinant of metabolic responses to exercise and provide evidence to the concept that a progressive reduction in liver glycogen might constitute a stimulus for the early free fatty acid response. |
| | |
Authors:
|
J M Lavoie; R Hélie; R Pitre; R Chaput |
Related Documents
:
|
9078277 - Regulation of glycogen synthase and phosphorylase during recovery from high-intensity e... 2132167 - Effect of swimming in thermal water on skeletal muscle, liver and heart glycogen. 1575047 - Glycogen breakdown in different human muscle fibre types during exhaustive exercise of ... 10567017 - Regulation of skeletal muscle glycogen phosphorylase and pdh during maximal intermitten... 11762557 - Pharmacokinetics of norelgestromin and ethinyl estradiol delivered by a contraceptive p... 8118637 - Refractoriness of eucapnic hyperventilation-induced bronchoconstriction in rabbits. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: International journal of sports medicine Volume: 8 ISSN: 0172-4622 ISO Abbreviation: Int J Sports Med Publication Date: 1987 Aug |
Date Detail:
|
Created Date: 1987-12-04 Completed Date: 1987-12-04 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 8008349 Medline TA: Int J Sports Med Country: GERMANY, WEST |
Other Details:
|
Languages: eng Pagination: 286-91 Citation Subset: IM |
Affiliation:
|
Department of Physical Education, University of Montreal, Canada. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Catecholamines / blood Fasting* / adverse effects Fatty Acids, Nonesterified / blood* Insulin / blood* Liver Glycogen / metabolism Male Physical Exertion* Rats Rats, Inbred Strains Time Factors |
| Chemical | |
Reg. No./Substance:
|
0/Catecholamines; 0/Fatty Acids, Nonesterified; 0/Liver Glycogen; 11061-68-0/Insulin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Review on sobrerol as a muco-modifying drug: experimental data and clinical findings in hypersecreto...
Next Document: A promising novel therapy for Achilles peritendinitis: double-blind comparison of glycosaminoglycan ...