Document Detail


FDG-PET scanning in the management of cancer of the oesophagus and oesophagogastric junction: early experience with 100 consecutive cases.
MedLine Citation:
PMID:  17312829     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The aim was to evaluate the impact of FDG-PET scan on tumour staging and management decisions in oesophageal cancer. METHODS: One-hundred consecutive patients referred for consideration of surgery underwent a whole body FDG-PET scan in addition to CT imaging. RESULTS: Based on CT scan, a curative approach could be considered in 62 patients. The PET scan altered regional nodal (N) staging in 16 patients overall, but did not alter management decisions. Metastatic status (M) was increased in 14 patients, with altered management in 10/62 (16%). Nine were downstaged, with management changed in 3/38 (8%). Seventeen patients underwent 19 additional tests to clarify findings on PET, in 15 patients (88%) the tests revealed no pathology. CONCLUSION: FDG-PET alters M stage in 23% of patients and may impact on surgical decision-making. The spurious investigations and cost of the high false-positive rate of further tests is of concern.
Authors:
V Malik; M Keogan; C Gilham; G Duffy; N Ravi; J V Reynolds
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Irish journal of medical science     Volume:  175     ISSN:  0021-1265     ISO Abbreviation:  Ir J Med Sci     Publication Date:    2006 Oct-Dec
Date Detail:
Created Date:  2007-02-22     Completed Date:  2007-11-02     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  7806864     Medline TA:  Ir J Med Sci     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  48-54     Citation Subset:  IM    
Affiliation:
Dept of Clinical Surgery, St James's Hospital and Trinity College Dublin.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Esophageal Neoplasms / pathology*,  radionuclide imaging*,  therapy
Esophagogastric Junction / pathology*,  radionuclide imaging*
Female
Fluorodeoxyglucose F18 / diagnostic use
Humans
Lymph Nodes
Male
Middle Aged
Neoplasm Staging
Positron-Emission Tomography*
Radiopharmaceuticals / diagnostic use
Chemical
Reg. No./Substance:
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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