Document Detail

FDA'S food ingredient approval process: Safety assurance based on scientific assessment.
MedLine Citation:
PMID:  18983884     Owner:  NLM     Status:  MEDLINE    
Fifty years ago, the Food and Drug Administration (FDA) began implementing new provisions of the Federal Food, Drug, and Cosmetic Act aimed at assuring the safety of new food additives before they enter the marketplace. Today, the agency's procedures for premarket evaluation of food additive safety have evolved into a scientifically rigorous, sound and dependable system whose objective and independent evaluations by FDA scientists assure that new food additives are safe for their intended uses before they arrive on the consumer's plate. Although controversy often surrounds food additives in the popular media and culture, and science-based challenges to FDA's decisions do arise, the agency's original safety judgments successfully withstand these challenges time and again. This article reviews the basic components of the FDA's decision-making process for evaluating the safety of new food additives, and identifies characteristics of this process that are central to assuring that FDA's decisions are marked by scientific rigor and high integrity, and can continue to be relied on by consumers.
Alan M Rulis; Joseph A Levitt
Related Documents :
12492104 - Medical devices: reclassification and codification of the absorbable polydioxanone surg...
11503724 - Medical device; exemption from premarket notification; class ii devices; barium enema r...
10069924 - The us food and drug administration investigational device exemptions (ide) and clinica...
11503864 - Clinical chemistry and clinical toxicology devices; classification of b-type natriureti...
10792644 - Probeliatrade mark pcr system for rapid detection of salmonella in milk powder and rico...
19209594 - Distribution patterns suggest biomagnification of halogenated 1'-methyl-1,2'-bipyrroles...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-11-01
Journal Detail:
Title:  Regulatory toxicology and pharmacology : RTP     Volume:  53     ISSN:  1096-0295     ISO Abbreviation:  Regul. Toxicol. Pharmacol.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-02     Completed Date:  2009-03-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8214983     Medline TA:  Regul Toxicol Pharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  20-31     Citation Subset:  IM    
Exponent, Inc., Center for Chemical Regulation and Food Safety, 1150 Connecticut Ave. NW, Suite 1100, Washington, DC 20036, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Consumer Product Safety / legislation & jurisprudence*
Decision Making
Food Additives / toxicity*
Food Analysis / methods
Food Supply / legislation & jurisprudence,  standards*
United States
United States Food and Drug Administration / legislation & jurisprudence*
Reg. No./Substance:
0/Food Additives

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Infectious bursal disease subviral particles displaying the foot-and-mouth disease virus major antig...
Next Document:  Oxidative stress and cognitive ability in adults with Down syndrome.