Document Detail

F(2)-Isoprostanes in soft oral tissues and degree of oral disability after mandibular third molar surgery.
MedLine Citation:
PMID:  22862975     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: The aim of this study was to test the value of F(2)-isoprostane (F(2)-IsoP) levels in the pericoronal gingiva as a potential predictor of oral disability after mandibular third molar (M3M) surgery.
STUDY DESIGN: Thirteen patients (5 male, 8 female) with partially impacted M3M were enrolled. Pericoronal soft tissues histology was obtained, gingival F(2)-IsoPs were measured by gas chromatography/negative-ion chemical ionization tandem mass spectrometry, and health-related quality of life (HRQOL) scores were assessed.
RESULTS: A variable degree of pericoronitis was evident before the M3M surgery, with a mean level of pericoronal F(2)-IsoPs of 634.8 ± 193.5 pg/mg of tissue. A significant positive correlation between pericoronal F(2)-IsoPs and HRQOL was observed in male (r(s) = 0.440; P = .0011), but not female (r(s) = -0.062; P = .5124) patients.
CONCLUSIONS: Levels of F(2)-IsoPs in the pericoronal soft tissues are correlated with the degree of oral disability after M3Ms surgery in male, but not female, patients.
Stefano Parrini; Glauco Chisci; Silvia Leoncini; Cinzia Signorini; Nila Volpi; Aniello Capuano; Lucia Ciccoli; Claudio De Felice
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology and oral radiology     Volume:  114     ISSN:  2212-4411     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101576782     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  344-9     Citation Subset:  D; IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Tuscan School of Dental Medicine, University of Siena, Siena, Italy.
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