Document Detail


F-18 FDG PET demonstrates crossed cerebellar diaschisis 20 years after stroke.
MedLine Citation:
PMID:  16622331     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Stroke produces an area of focal damage and distant areas of reduced blood blow and metabolism termed diaschisis. Tc-99m ECD and HMPAO brain SPECT have demonstrated crossed cerebellar diaschisis (CCD) in patients with cerebral cortical infarct. SPECT findings reflect abnormal cerebral blood flow. CCD as shown on F-18 FDG PET reflects abnormal reflects glucose metabolism. We present the case of a patient with laryngeal cancer who also had a stroke in the left cerebral hemisphere involving the territory of the middle cerebral artery 20 years ago. This patient underwent PET, including the head and neck. A current brain F-18 FDG PET exhibited hypometabolism in the contralateral cerebellum (CCD) as well as hypometabolism of the primary insult in the left cerebral hemisphere. These findings reflect partial impairment or diminished glucose metabolism in the primary insult to the cerebrum and contralateral cerebellum. In addition, this patient illustrates that on PET imaging, CCD could be demonstrated 20 years after a stroke.
Authors:
Wei-Jen Shih; Wen-Sheng Huang; Primo P Milan
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  31     ISSN:  0363-9762     ISO Abbreviation:  Clin Nucl Med     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-04-19     Completed Date:  2006-09-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  259-61     Citation Subset:  IM    
Affiliation:
Nuclear Medicine Service, Lexington VA Medical Center, KY, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Brain Ischemia / etiology*,  radionuclide imaging*
Cerebellar Diseases / etiology*,  radionuclide imaging*
Cerebellum / blood supply,  radionuclide imaging
Fluorodeoxyglucose F18 / diagnostic use*
Humans
Incidental Findings
Laryngeal Neoplasms / radionuclide imaging
Longitudinal Studies
Male
Positron-Emission Tomography / methods
Radiopharmaceuticals / diagnostic use
Stroke / complications*,  radionuclide imaging*
Time Factors
Chemical
Reg. No./Substance:
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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