Document Detail

Eye tumors and other lesions among beagles given 90Sr or 226Ra.
MedLine Citation:
PMID:  8106256     Owner:  NLM     Status:  MEDLINE    
Analysis of eye tumors and other eye lesions among beagles given either 90Sr or 226Ra, and among control animals, indicated that intraocular tumors in excess of the rate for our control animals were not associated with radiation from incorporated 90Sr + 90Y. It is unequivocal that eye melanomas were produced by injected 226Ra. Intraocular neoplasia, hyperplasia, hyperpigmentation, and melanosis in the eye all occurred in our control beagles given no radioactivity; however, tumor experience as currently reported for different beagle colonies may not be directly comparable because of differing rates of discovery, nonuniform nomenclature, and varying criteria for classification of lesions with their discordant interpretation by different pathologists.
R D Lloyd; G N Taylor; W Angus; F W Bruenger; S C Miller
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Health physics     Volume:  66     ISSN:  0017-9078     ISO Abbreviation:  Health Phys     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-03-24     Completed Date:  1994-03-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985093R     Medline TA:  Health Phys     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  346-9     Citation Subset:  IM    
Radiobiology Laboratory, University of Utah School of Medicine, Salt Lake City 84112.
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MeSH Terms
Eye Diseases / etiology*
Eye Neoplasms / etiology*
Melanoma, Experimental / etiology
Radium / administration & dosage*
Strontium Radioisotopes / administration & dosage*
Reg. No./Substance:
0/Strontium Radioisotopes; 7440-14-4/Radium

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