| Eye preservation tectonic graft using glycerol-preserved donor cornea. | |
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MedLine Citation:
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PMID: 22975657 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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AimsTo report the surgical outcome of tectonic graft using glycerol-preserved donor corneas to treat perforated keratitis.MethodsThe medical records were reviewed of all patients treated for perforated keratitis using glycerol-preserved corneas at a single institution between 1 July 2004 and 31 June 2010. The clinical features, precipitating factors, adjuvant therapies, and therapeutic outcomes were analyzed. Success was defined as re-epithelialization of the ocular surface without evisceration.ResultsFourteen eyes from 14 patients (6 male and 8 female) were included. Age ranged from 58 to 84 years (average, 70.71±8.52 years) and the follow-up time ranged from 7 to 56 months (mean, 25.35±16.84 months). The culture results showed five bacterial infections, five cases of fungal keratitis, and one mixed infection; the culture results were negative for three patients. Satisfactory anatomical integrity was obtained in eight grafts (57.14%) that healed with neovascularization. Six grafts (48.85%) showed delayed re-epithelialization and were repaired with conjunctival flaps to maintain ocular surface integrity. Three patients developed secondary glaucoma and received trans-scleral cyclophotocoagulation. Thirteen patients had satisfactory anatomical integrity without evisceration or exenteration, while one patient received evisceration at 39-month follow-up because of intractable glaucoma.ConclusionsGlycerol-preserved donor corneas combined with anterior vitrectomy with or without conjunctival flaps may be effective substitutes for evisceration surgery in patients with perforated keratitis.Eye advance online publication, 14 September 2012; doi:10.1038/eye.2012.192. |
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Authors:
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H-C Lin; S J Ong; A-N Chao |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-9-14 |
Journal Detail:
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Title: Eye (London, England) Volume: - ISSN: 1476-5454 ISO Abbreviation: Eye (Lond) Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-9-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8703986 Medline TA: Eye (Lond) Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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