Document Detail

Exudative retinal detachment following photocoagulation in older premature infants for retinopathy of prematurity: description and management.
MedLine Citation:
PMID:  23881225     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To describe exudative retinal detachment following laser photocoagulation after 40 weeks of postmenstrual age (PMA) for retinopathy of prematurity in premature infants, its medical management, and outcomes.
METHODS: Two pediatric vitreoretinal surgeons at 2 different quaternary care institutions retrospectively identified children who received laser photocoagulation after 40 weeks of PMA and subsequently developed exudative detachment. Hospital course, management, and outcomes were identified.
RESULTS: Three infants were identified that developed exudative retinal detachments following laser photocoagulation for retinopathy of prematurity after 40 weeks of PMA. The average gestational age was 25 weeks with an average birth weight of 650 g. All babies were Zone II at initial examination and developed Stage 3 with pre-plus or plus disease after 40 weeks of PMA (average 42 weeks of PMA). Therapy consisted of topical cyclogyl (0.5%) and topical prednisolone acetate (1%) to the affected eyes and intravenous dexamethasone in all cases. The exudative retinal detachments resolved by 50 weeks of PMA in all infants. Hard exudates following resolution were found in all eyes. Two eyes demonstrated temporal macular dragging.
CONCLUSION: Premature infants who require laser photocoagulation for retinopathy of prematurity at >40 weeks of PMA may be predisposed to develop exudative retinal detachments. In the absence of identifiable traction, systemic corticosteroid use can be considered to achieve favorable anatomic outcomes.
Darius M Moshfeghi; Ruwan A Silva; Audina M Berrocal
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Publication Detail:
Type:  Case Reports; Historical Article; Journal Article    
Journal Detail:
Title:  Retina (Philadelphia, Pa.)     Volume:  34     ISSN:  1539-2864     ISO Abbreviation:  Retina (Philadelphia, Pa.)     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2013-12-23     Completed Date:  2014-04-16     Revised Date:  2014-09-05    
Medline Journal Info:
Nlm Unique ID:  8309919     Medline TA:  Retina     Country:  United States    
Other Details:
Languages:  eng     Pagination:  83-6     Citation Subset:  IM    
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MeSH Terms
Administration, Topical
Cyclopentolate / therapeutic use
Exudates and Transudates
Gestational Age
History, Ancient
Infant, Extremely Low Birth Weight
Infant, Newborn
Infant, Premature*
Infusions, Intravenous
Laser Coagulation / adverse effects*
Mydriatics / therapeutic use
Prednisolone / analogs & derivatives,  therapeutic use
Retinal Detachment / drug therapy,  etiology*,  physiopathology
Retinopathy of Prematurity / surgery*
Reg. No./Substance:
0/Mydriatics; 52-21-1/prednisolone acetate; 9PHQ9Y1OLM/Prednisolone; I76F4SHP7J/Cyclopentolate
Comment In:
Retina. 2014 Aug;34(8):e22-3   [PMID:  25011030 ]
Retina. 2014 Aug;34(8):e23-4   [PMID:  25054346 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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