Document Detail

Extremely well differentiated squamous cell carcinoma of the breast. Report of a case with a comparative study of an epidermal cyst.
MedLine Citation:
PMID:  8693894     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Although the cytologic diagnosis of malignancy by fine needle aspiration is easy in cases of moderately to poorly differentiated squamous cell carcinoma in various organs, it is not always easy in cases of the well-differentiated type. CASE: A 46-year-old female presented with a slowly growing mass in the right breast; it was diagnosed as an extremely well differentiated squamous cell carcinoma. The diagnosis of malignancy was initially not established by fine needle aspiration cytology because of minimal cellular atypia. The smear contained many squamous cells, mainly of the superficial type, with little cellular atypia, in a background of horny material. However, neither anuclear superficial cells nor granular cells were found. CONCLUSION: Absence of anuclear keratinized cells and granular cells is probably a helpful finding for distinguishing squamous cell carcinoma from epidermal cyst in the breast region.
T Motoyama; H Watanabe
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article    
Journal Detail:
Title:  Acta cytologica     Volume:  40     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    1996 Jul-Aug
Date Detail:
Created Date:  1996-08-26     Completed Date:  1996-08-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  729-33     Citation Subset:  IM    
Department of Pathology, Niigata University School of Medicine, Japan.
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MeSH Terms
Biopsy, Needle
Breast Diseases / pathology*
Breast Neoplasms / pathology*
Carcinoma, Squamous Cell / pathology*
Coloring Agents
Diagnosis, Differential
Epidermal Cyst / pathology*
Middle Aged
Reg. No./Substance:
0/Coloring Agents; 68238-35-7/Keratins

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