Document Detail


Extremely low nerve growth facior (NGF) activity of sea snake (Hydrophiidae) venoms.
MedLine Citation:
PMID:  12503884     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sea snake venoms contain less protein than those of land snakes (Toom et al., 1969). Sea snake venoms lack arginine ester hydrolyzing activity, whereas those of Crotalidae and Viperidae have such activity (Tu et al., 1966). Sea snakes live in salty water, and their venoms may be different from those of land snakes. Because of the difficulty in obtaining sea snake venoms, information about sea snake venoms is quite incomplete. NGF is commonly present in the venoms of land snakes such as Elapidae, Viperidae, and Crotalidae (Cohen and Levi-Montalcini, 1956; Lipps, 2002). It is therefore of interest to investigate the presence or absence of NGF in sea snake venoms. In order to investigate the presence or absence of NGF, five sea snake venoms were selected. Lapemis hardwickii (Hardwick's sea snake) and Acalyptophis peronii venom were obtained from the Gulf of Thailand. Hydrophis cyanocinctus (common sea snake) and Enhydrina schistosa (beaked sea snake) venom were obtained from the Strait of Malacca. Laticauda semifasciata (broad band blue sea snake) venom was also examined and the venom was obtained from Gato Island in the Philippines.
Authors:
Khafizova Mariam; Anthony T Tu
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of natural toxins     Volume:  11     ISSN:  1058-8108     ISO Abbreviation:  J Nat Toxins     Publication Date:  2002 Dec 
Date Detail:
Created Date:  2002-12-30     Completed Date:  2003-05-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9208016     Medline TA:  J Nat Toxins     Country:  United States    
Other Details:
Languages:  eng     Pagination:  393-8     Citation Subset:  IM    
Affiliation:
Department of Biochemistry, Uzbekistan Academy of Science, Tashkent, Uzbekistan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Chick Embryo
Cobra
Cobra Venoms / biosynthesis
Ganglia, Spinal / drug effects
Hydrophid Venoms / metabolism*
Hydrophidae*
Nerve Growth Factor / biosynthesis*,  pharmacology
Neurotoxins / biosynthesis
Chemical
Reg. No./Substance:
0/Cobra Venoms; 0/Hydrophid Venoms; 0/Neurotoxins; 9061-61-4/Nerve Growth Factor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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