| Extremely Low Frequency Magnetic Fields Do Not Elicit Oxidative Stress in MCF10A Cells. | |
| | |
MedLine Citation:
|
PMID: 22302048 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
The aim of this study was to determine whether extremely low frequency magnetic fields (ELF-MF) could affect intracellular reactive oxygen species (ROS) levels and antioxidant enzyme activity. After MCF10A human breast epithelial cells were exposed to 1 mT of 60 Hz ELF-MF for 4 hours, intracellular ROS level, superoxide dismutase (SOD) activity, and reduced to oxidized glutathione (GSH/GSSG) ratio were measured. The cells exposed to ELF-MF did not evidence statistically significant changes in the above-mentioned biological parameters as compared to either the incubator controls or sham-exposed cells. By way of contrast, the IR-exposed cells exhibited marked changes in ROS level, SOD activity, and GSH/GSSG ratio. When we assessed morphological changes and senescence-associated beta-galactosidase (SA-β-Gal) activity, only the IR-exposed cells were positive. According to our results, it could be concluded that ELF-MF has no effect on intracellular ROS level, SOD activity, and GSH/GSSG ratio under our exposure condition. |
| | |
Authors:
|
Mi-Na Hong; Na-Kyung Han; Hyung-Chul Lee; Young-Kyu Ko; Sung-Gil Chi; Yun-Sil Lee; Yoon-Myung Gimm; Sung-Ho Myung; Jae-Seon Lee |
Related Documents
:
|
2999448 - Effects of sodium n-butyrate on entry into s phase in resting rat 3y1 cells infected wi... 22412948 - Bantam is required for optic lobe development and glial cell proliferation. 18656418 - Cell population tracking and lineage construction with spatiotemporal context. 2446768 - Fractionation of k-562 cells on the basis of their surface properties by partitioning i... 12133548 - Renal cell carcinoma related novel gene, gylz-rcc18: cloning and functional studies. 410778 - Functional modifications of the translational system in bacillus subtilis during sporul... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of radiation research Volume: 53 ISSN: 1349-9157 ISO Abbreviation: J. Radiat. Res. Publication Date: 2012 |
Date Detail:
|
Created Date: 2012-02-03 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0376611 Medline TA: J Radiat Res (Tokyo) Country: Japan |
Other Details:
|
Languages: eng Pagination: 79-86 Citation Subset: IM |
Affiliation:
|
Division of Radiation Cancer Research, Korea Institute of Radiological & Medical Sciences. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Overexpression of cks1 increases the radiotherapy resistance of esophageal squamous cell carcinoma.
Next Document: Evaluation of the relative biological effectiveness of carbon ion beams in the cerebellum using the ...