Document Detail

Extreme hyperbilirubinemia in newborn infants.
MedLine Citation:
PMID:  16708139     Owner:  NLM     Status:  MEDLINE    
This study was undertaken to determine the frequency and investigate the etiology of extreme hyperbilirubinemia (total serum bilirubin [TSB]>or=25 mg/dL [428 micromol/L]) in newborns admitted to a neonatal intensive care unit in southern Turkey. The charts of 93 term and near-term infants admitted with TSB levels of 25 mg/dL (428 micromol/L) or greater in the first 30 days after birth were retrospectively reviewed. During the 4.5-year study period, 774 infants were admitted to our unit with neonatal jaundice. Ninety-three (12%) of these infants had TSB levels of 25 mg/dL (428 micromol/L) or greater. The mean TSB level in the 93 cases was 30.1+/-5.7 mg/dL (514.7+/-97.5 micromol/L), and the peak levels ranged from 25.0 to 57.4 mg/dL (428-981.5 micromol/L). Thirty-three (35.5%) of the 93 babies had TSB levels of 30 mg/dL (513 micromol/L) or greater. Eighty-nine of 93 infants were being exclusively breast-fed. Nineteen babies were isoimmunized, 7 were bacteremic, 2 of the 39 babies tested for glucose-6-phosphate dehydrogenase had this enzyme deficiency, and 1 of the 71 infants tested for thyroid function had hypothyroidism. No cause for extreme hyperbilirubinemia was found in 61 (65.6%) cases.
Filiz Tiker; Hande Gulcan; Hasan Kilicdag; Aylin Tarcan; Berkan Gurakan
Related Documents :
8252149 - The clinical significance of abo blood group incompatibility.
15102359 - Molecular basis of bilirubin-induced neurotoxicity.
11428729 - Kernicterus in full-term infants--united states, 1994-1998.
8838769 - Prenatal diagnosis of diffuse mesangial glomerulosclerosis by ultrasonography: a longit...
22053549 - Ultrasonographic assessment of kidney dimensions in first six months of life.
19030259 - Estimation of bilirubin using bilichektrade mark, a transcutaneous bilirubin measuremen...
19886849 - Assessing early communication behaviours: structure and validity of the communication a...
23582679 - Pathophysiology of persistent pulmonary hypertension of the newborn: impact of the peri...
9164769 - Maternal and perinatal risk factors for later delinquency.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical pediatrics     Volume:  45     ISSN:  0009-9228     ISO Abbreviation:  Clin Pediatr (Phila)     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-05-18     Completed Date:  2006-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372606     Medline TA:  Clin Pediatr (Phila)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  257-61     Citation Subset:  AIM; IM    
Department of Pediatrics, Division of Neonatology, Baskent University Faculty of Medicine, Adana, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Bilirubin / blood*
Blood Group Incompatibility / complications*
Gestational Age
Glucosephosphate Dehydrogenase Deficiency / complications*
Infant, Newborn
Intensive Care Units, Neonatal
Jaundice, Neonatal / drug therapy,  etiology*
Medical Records
Retrospective Studies
Turkey / epidemiology
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Variability in the management of childhood constipation.
Next Document:  Preschool vision screening in pediatric practices.