| Extreme hyperbilirubinemia in newborn infants. | |
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MedLine Citation:
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PMID: 16708139 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study was undertaken to determine the frequency and investigate the etiology of extreme hyperbilirubinemia (total serum bilirubin [TSB]>or=25 mg/dL [428 micromol/L]) in newborns admitted to a neonatal intensive care unit in southern Turkey. The charts of 93 term and near-term infants admitted with TSB levels of 25 mg/dL (428 micromol/L) or greater in the first 30 days after birth were retrospectively reviewed. During the 4.5-year study period, 774 infants were admitted to our unit with neonatal jaundice. Ninety-three (12%) of these infants had TSB levels of 25 mg/dL (428 micromol/L) or greater. The mean TSB level in the 93 cases was 30.1+/-5.7 mg/dL (514.7+/-97.5 micromol/L), and the peak levels ranged from 25.0 to 57.4 mg/dL (428-981.5 micromol/L). Thirty-three (35.5%) of the 93 babies had TSB levels of 30 mg/dL (513 micromol/L) or greater. Eighty-nine of 93 infants were being exclusively breast-fed. Nineteen babies were isoimmunized, 7 were bacteremic, 2 of the 39 babies tested for glucose-6-phosphate dehydrogenase had this enzyme deficiency, and 1 of the 71 infants tested for thyroid function had hypothyroidism. No cause for extreme hyperbilirubinemia was found in 61 (65.6%) cases. |
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Authors:
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Filiz Tiker; Hande Gulcan; Hasan Kilicdag; Aylin Tarcan; Berkan Gurakan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical pediatrics Volume: 45 ISSN: 0009-9228 ISO Abbreviation: Clin Pediatr (Phila) Publication Date: 2006 Apr |
Date Detail:
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Created Date: 2006-05-18 Completed Date: 2006-09-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372606 Medline TA: Clin Pediatr (Phila) Country: United States |
Other Details:
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Languages: eng Pagination: 257-61 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatrics, Division of Neonatology, Baskent University Faculty of Medicine, Adana, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bilirubin
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blood* Blood Group Incompatibility / complications* Female Gestational Age Glucosephosphate Dehydrogenase Deficiency / complications* Humans Infant, Newborn Intensive Care Units, Neonatal Jaundice, Neonatal / drug therapy, etiology* Male Medical Records Phototherapy Retrospective Studies Turkey / epidemiology |
| Chemical | |
Reg. No./Substance:
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635-65-4/Bilirubin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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