Document Detail


Extreme hyperbilirubinemia in newborn infants.
MedLine Citation:
PMID:  16708139     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study was undertaken to determine the frequency and investigate the etiology of extreme hyperbilirubinemia (total serum bilirubin [TSB]>or=25 mg/dL [428 micromol/L]) in newborns admitted to a neonatal intensive care unit in southern Turkey. The charts of 93 term and near-term infants admitted with TSB levels of 25 mg/dL (428 micromol/L) or greater in the first 30 days after birth were retrospectively reviewed. During the 4.5-year study period, 774 infants were admitted to our unit with neonatal jaundice. Ninety-three (12%) of these infants had TSB levels of 25 mg/dL (428 micromol/L) or greater. The mean TSB level in the 93 cases was 30.1+/-5.7 mg/dL (514.7+/-97.5 micromol/L), and the peak levels ranged from 25.0 to 57.4 mg/dL (428-981.5 micromol/L). Thirty-three (35.5%) of the 93 babies had TSB levels of 30 mg/dL (513 micromol/L) or greater. Eighty-nine of 93 infants were being exclusively breast-fed. Nineteen babies were isoimmunized, 7 were bacteremic, 2 of the 39 babies tested for glucose-6-phosphate dehydrogenase had this enzyme deficiency, and 1 of the 71 infants tested for thyroid function had hypothyroidism. No cause for extreme hyperbilirubinemia was found in 61 (65.6%) cases.
Authors:
Filiz Tiker; Hande Gulcan; Hasan Kilicdag; Aylin Tarcan; Berkan Gurakan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical pediatrics     Volume:  45     ISSN:  0009-9228     ISO Abbreviation:  Clin Pediatr (Phila)     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-05-18     Completed Date:  2006-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372606     Medline TA:  Clin Pediatr (Phila)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  257-61     Citation Subset:  AIM; IM    
Affiliation:
Department of Pediatrics, Division of Neonatology, Baskent University Faculty of Medicine, Adana, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Bilirubin / blood*
Blood Group Incompatibility / complications*
Female
Gestational Age
Glucosephosphate Dehydrogenase Deficiency / complications*
Humans
Infant, Newborn
Intensive Care Units, Neonatal
Jaundice, Neonatal / drug therapy,  etiology*
Male
Medical Records
Phototherapy
Retrospective Studies
Turkey / epidemiology
Chemical
Reg. No./Substance:
635-65-4/Bilirubin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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