| Extreme gestational starvation ketoacidosis: case report and review of pathophysiology. | |
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MedLine Citation:
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PMID: 1519609 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case of severe starvation ketoacidosis developing during pregnancy is presented. The insulinopenic/insulin-resistant state found during fasting in late gestation predisposes to ketosis. Superimposition of stress hormones, which further augment lipolysis, exacerbates the degree of ketoacidosis. In our patient, gestational diabetes, twin pregnancies, preterm labor, and occult infection were factors that contributed to severe starvation ketoacidosis. Diagnosis was delayed because starvation ketosis is not generally considered to be a cause of severe acidosis, and because the anion gap was not elevated. Improved understanding of the complex fuel metabolism during pregnancy should aid in prevention, early recognition, and appropriate therapy of this condition. |
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Authors:
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C A Mahoney |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of kidney diseases : the official journal of the National Kidney Foundation Volume: 20 ISSN: 0272-6386 ISO Abbreviation: Am. J. Kidney Dis. Publication Date: 1992 Sep |
Date Detail:
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Created Date: 1992-10-08 Completed Date: 1992-10-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8110075 Medline TA: Am J Kidney Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 276-80 Citation Subset: IM |
Affiliation:
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Department of Medicine, Stanford University School of Medicine, CA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Diabetes, Gestational* / diagnosis, physiopathology Diabetic Ketoacidosis* / diagnosis, physiopathology Female Humans Pregnancy Pregnancy, Multiple Starvation / physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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