| Extreme efficacy of intravenous immunoglobulin therapy for severe burning pain in a patient with small fiber neuropathy associated with primary Sjögren's syndrome. | |
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MedLine Citation:
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PMID: 19458906 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Neurological involvement occurs in approximately 20% of patients with primary Sjögren's syndrome. Although neurological symptoms can affect the peripheral nervous system and the central nervous system, the most frequent symptom is polyneuropathy. Small fiber neuropathy (SFN) is a form of painful peripheral polyneuropathy that is common in patients with diabetic neuropathy, but may also occur in toxic, infectious, or immune-mediated neuropathy. We show here a patient with Sjögren's syndrome who developed SFN and was treated with intravenous immunoglobulin (IVIG) therapy, which was immediately and extremely effective. Because of the efficacy of IVIG therapy, we propose that direct immune-mediated mechanisms may be involved in the pathogenesis of SFN complicated by Sjögren's syndrome. |
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Authors:
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Daisuke Wakasugi; Takashi Kato; Takahisa Gono; Eiichi Ito; Hiroyuki Nodera; Yasushi Kawaguchi; Hisashi Yamanaka; Masako Hara |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-05-22 |
Journal Detail:
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Title: Modern rheumatology / the Japan Rheumatism Association Volume: 19 ISSN: 1439-7595 ISO Abbreviation: Mod Rheumatol Publication Date: 2009 |
Date Detail:
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Created Date: 2009-08-04 Completed Date: 2009-11-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100959226 Medline TA: Mod Rheumatol Country: Japan |
Other Details:
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Languages: eng Pagination: 437-40 Citation Subset: IM |
Affiliation:
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Department of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo 162-0054, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Humans Immunoglobulins, Intravenous / therapeutic use* Immunologic Factors / therapeutic use* Pain / drug therapy, etiology, pathology* Pain Measurement Paresthesia / drug therapy, etiology, pathology* Peripheral Nervous System Diseases / drug therapy, etiology, pathology* Sjogren's Syndrome / complications, drug therapy, pathology* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulins, Intravenous; 0/Immunologic Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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