Document Detail

Extravasation of Liposomal Doxorubicin Induces Irritant Reaction without Vesicant Injury.
MedLine Citation:
PMID:  22493389     Owner:  NLM     Status:  In-Data-Review    
Anthracycline extravasation is an uncommon but very serious complication. Very few data are available in the literature concerning the consequences and the management of extravasation of liposomal doxorubicin. This report describes the cases of two patients with liposomal doxorubicin extravasation who developed irritant reaction without vesicant or necrotic lesions. It is concordant with other cases described in the literature and suggests that extravasation of liposomal doxorubicin can be relatively well tolerated. The process applied to extravasations of irritant and non-vesicant agents could be used to manage extravasations of liposomal doxorubicin.
Elsa Curtit; Loïc Chaigneau; Julien Pauchot; Thierry Nguyen; Virginie Nerich; Fernando Bazan; Antoine Thiery-Vuillemin; Martin Demarchi; Xavier Pivot; Cristian Villanueva
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anticancer research     Volume:  32     ISSN:  1791-7530     ISO Abbreviation:  Anticancer Res.     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-04-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8102988     Medline TA:  Anticancer Res     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  1481-3     Citation Subset:  IM    
Department of Medical Oncology, Jean Minjoz University Hospital, 3, bd Alexandre Fleming, 25030 Besancon Cedex France.
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