Document Detail

Extrapyramidal side effects in chlorpromazine recipients: emergence according to benztropine prophylaxis.
MedLine Citation:
PMID:  889418     Owner:  NLM     Status:  MEDLINE    
The frequency of extrapyramidal symptoms (EPS) attributed to chlorpromazine among 86 patients who received benztropine for the prevention of EPS (9.3%) was similar to that of the 568 patients who received chlorpromazine alone (10.6%). The data in this small sample indicated that the prophylactic use of benztropine had no effect in reducing the rate of EPS.
C Swett; J O Cole; S Shapiro; D Slone
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Archives of general psychiatry     Volume:  34     ISSN:  0003-990X     ISO Abbreviation:  Arch. Gen. Psychiatry     Publication Date:  1977 Aug 
Date Detail:
Created Date:  1977-09-29     Completed Date:  1977-09-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372435     Medline TA:  Arch Gen Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  942-3     Citation Subset:  AIM; IM    
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MeSH Terms
Affective Disorders, Psychotic / drug therapy
Basal Ganglia Diseases / chemically induced,  prevention & control*
Benztropine / therapeutic use*
Chlorpromazine / administration & dosage,  adverse effects*
Drug Therapy, Combination
Personality Disorders / drug therapy
Schizophrenia / drug therapy
Tropanes / therapeutic use*
Reg. No./Substance:
0/Tropanes; 50-53-3/Chlorpromazine; 86-13-5/Benztropine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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