| Extrapontine myelinolysis in a child with nephrotic syndrome. | |
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MedLine Citation:
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PMID: 20610127 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Extrapontine myelinolysis is rare in children. We describe a 6-year-old girl with nephrotic syndrome who presented with symptomatic hyponatremia, and who developed acute quadriparesis with pseudobulbar palsy during rapid correction of the hyponatremia. Cranial magnetic resonance imaging demonstrated bilateral, symmetric basal ganglia lesions (extrapontine myelinolysis). The extrapontine myelinolysis was caused by rapid correction of severe and prolonged hyponatremia with intravenous 3% sodium chloride. The child demonstrated complete neurologic recovery. Prevention of this rare condition involves recognizing patients at risk for the disorder, and avoiding rapid correction of severe and prolonged hyponatremia. To the best of our knowledge, this is the first case report of extrapontine myelinolysis in a child with nephrotic syndrome. |
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Authors:
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Milind S Tullu; Isha Deshmukh; Mamta N Muranjan; Archana S Kher; Keya R Lahiri |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric neurology Volume: 43 ISSN: 1873-5150 ISO Abbreviation: Pediatr. Neurol. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-08 Completed Date: 2011-01-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8508183 Medline TA: Pediatr Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 139-41 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Pediatrics, Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Maharashtra, Mumbai, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Basal Ganglia
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pathology Child Diffusion Magnetic Resonance Imaging / methods Female Humans Myelinolysis, Central Pontine / diagnosis, etiology* Nephrotic Syndrome / complications*, diagnosis Water-Electrolyte Balance / physiology |
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