Document Detail

Extranodal marginal zone B cell lymphoma of MALT type with extensive plasma cell differentiation in a man with Hashimoto's thyroiditis.
MedLine Citation:
PMID:  22673712     Owner:  NLM     Status:  MEDLINE    
Primary thyroid gland lymphomas are uncommon tumours that occur in the setting of lymphocytic thyroiditis or Hashimoto's disease in almost all cases. Rarely these tumours show extensive plasmacytic differentiation. In these conditions, a distinction between an inflammatory thyroid infiltrate and extramedullary plasmacytoma may be extremely difficult and precise criteria and ancillary techniques are necessary for a correct diagnosis. The authors report a case of mucosa associated lymphoid tissue (MALT) lymphoma of the thyroid gland in a 69-year-old Iranian man with Hashimoto's thyroiditis which was diagnosed by means of immunohistochemical stains. This case demonstrates that histology may not distinguish between extramedullary plasmacytoma and MALT lymphoma of the thyroid gland and the use of immunohistochemical staining stains were essential to prove definite diagnosis.
Fariba Binesh; Ali Akhavan; Hossein Navabii
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2011-11-01
Journal Detail:
Title:  BMJ case reports     Volume:  2011     ISSN:  1757-790X     ISO Abbreviation:  BMJ Case Rep     Publication Date:  2011  
Date Detail:
Created Date:  2012-06-07     Completed Date:  2013-08-26     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  101526291     Medline TA:  BMJ Case Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  IM    
Pathology Department, Yazd Shahid Sadoghi University, Yazd, Iran, Islamic Republic of Iran.
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MeSH Terms
Cell Differentiation
Hashimoto Disease / complications*
Lymphoma, B-Cell, Marginal Zone / complications*,  pathology*
Plasma Cells / pathology*
Thyroid Neoplasms / complications*,  pathology*

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