| Extranodal cytotoxic T-cell lymphoma in a patient with X-linked agammaglobulinaemia. | |
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MedLine Citation:
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PMID: 11699214 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This report documents the occurrence of an extranodal cytotoxic peripheral T-cell lymphoma (PTCL) in a patient with X-linked agammaglobulinaemia (XLA). The diagnosis was based on the immunohistochemical detection of T-cell antigens and of the cytotoxic proteins TIA1 and Granzyme B in the tumour cells. This report provides further evidence that cytotoxic lymphomas are part of the differential diagnosis of neoplasia in patients with immunodeficiencies. |
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Authors:
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P Kanavaros; D Rontogianni; D Hrissovergi; A Efthimiadoy; T Argyrakos; K Mastoris; K Stefanaki |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Leukemia & lymphoma Volume: 42 ISSN: 1042-8194 ISO Abbreviation: Leuk. Lymphoma Publication Date: 2001 Jun |
Date Detail:
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Created Date: 2001-11-08 Completed Date: 2002-05-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9007422 Medline TA: Leuk Lymphoma Country: Switzerland |
Other Details:
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Languages: eng Pagination: 235-8 Citation Subset: IM |
Affiliation:
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Department of Histology, Medical Faculty, University of Thessalia, Hellas. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Agammaglobulinemia / complications*, genetics Granzymes Humans Immunohistochemistry Lymphoma, T-Cell / etiology, metabolism, pathology* Male Membrane Proteins / analysis Poly(A)-Binding Proteins Proteins* RNA-Binding Proteins / analysis Serine Endopeptidases / analysis T-Lymphocytes, Cytotoxic / pathology* X Chromosome* |
| Chemical | |
Reg. No./Substance:
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0/Membrane Proteins; 0/Poly(A)-Binding Proteins; 0/Proteins; 0/RNA-Binding Proteins; 145138-44-9/TIA1 protein, human; EC 3.4.21.-/GZMB protein, human; EC 3.4.21.-/Granzymes; EC 3.4.21.-/Serine Endopeptidases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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