Document Detail

Extraneural metastasis of glioblastoma multiforme presenting as an unusual neck mass.
MedLine Citation:
PMID:  22639711     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Glioblastoma multiforme (GBM) is the most aggressive intracranial tumor and it commonly spreads by direct extension and infiltration into the adjacent brain tissue and along the white matter tract. The metastatic spread of GBM outside of the central nervous system (CNS) is rare. The possible mechanisms of extraneural metastasis of the GBM have been suggested. They include the lymphatic spread, the venous invasion and the direct invasion through dura and bone. We experienced a 46-year-old man who had extraneural metastasis of the GBM on his left neck. The patient was treated with surgery for 5 times, radiotherapy and chemotherapy. He had survived 6 years since first diagnosed. Although the exact mechanism of the extraneural metastasis is not well understood, this present case shows the possibility of extraneural metastasis of the GBM, especially in patients with long survival.
Young Jun Seo; Won Ho Cho; Dong Wan Kang; Seung Heon Cha
Publication Detail:
Type:  Journal Article     Date:  2012-03-31
Journal Detail:
Title:  Journal of Korean Neurosurgical Society     Volume:  51     ISSN:  1598-7876     ISO Abbreviation:  J Korean Neurosurg Soc     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-05-28     Completed Date:  2012-08-23     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  101467054     Medline TA:  J Korean Neurosurg Soc     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  147-50     Citation Subset:  -    
Department of Neurosurgery & Medical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
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