Document Detail

Extraneural metastases of astrocytomas and glioblastomas: clinicopathological study of two cases and review of literature.
MedLine Citation:
PMID:  6985826     Owner:  NLM     Status:  MEDLINE    
Two cases of intracranial gliomas with extraneural metastases are described. Case 1, studied with biopsy material only, was a left malignant astrocytoma from the area of the rolandic fissure with right cervical lymph nodes metastases in a 43-year-old man. Case 2 was a left temporal malignant astrocytoma in a 21-year-old woman. Fifteen days after craniotomy, a left submandibular lymph node metastasis appeared. Forty days after surgery, a ventriculoperitoneal shunt was performed. Fifty-four days after surgery, the patient died. Autopsy revealed three liver metastases. Our review of the literature consists of 72 autopsy cases with extraneural deposits. Thos metastases occurred mainly in adults (63/72) and among men (46/72). The primary glioma was supratentorial in 67 cases. Metastases were mainly pulmonary and pleural. The majority of patients (82.8%) died within 2 years after onset of symptoms. In 8 of the cases, metastasis developed without any craniotomy and in 8 other cases, through a shunt.
B Pasquier; D Pasquier; A N'Golet; M H Panh; P Couderc
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Cancer     Volume:  45     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1980 Jan 
Date Detail:
Created Date:  1980-03-24     Completed Date:  1980-03-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  112-25     Citation Subset:  AIM; IM    
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MeSH Terms
Astrocytoma / pathology,  secondary*
Brain Neoplasms*
Glioma / pathology,  secondary*
Lymphatic Metastasis / pathology
Meningeal Neoplasms / pathology,  secondary*
Middle Aged
Neoplasm Seeding

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