| Extramedullary haematopoiesis in liver of sudden infant death cases. | |
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MedLine Citation:
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PMID: 17008039 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: To determine the frequency of extramedullary haematopoiesis (EMH) in sudden infant death and control cases, and to provide descriptive data on extramedullary haematopoietic islands and diffuse cells. METHODS: The study was carried out in 51 SIDS and 102 non-SIDS cases. Liver-tissue sections were stained with haematoxylin and eosin, and immunohistochemistry was done with streptavidin-biotin-peroxidase complexes by Polyclonal Haemoglobin "A" antibody. The prevalence of data was estimated statistically by Pearson chi-square test, descriptive statistics, and Kruskal-Wallis test. RESULTS: The Pearson chi-square values (CI: 95%; OR: 0.071-0.49; p: 0.0474) show higher frequency of EMH islands in SIDS than in controls. The number of diffuse extramedullary haematopoetic cells was higher in SIDS cases compared to non-SIDS (p=0.017). CONCLUSIONS: EMH is a frequent finding in SIDS cases, and this may be a consequence of anaemia associated with intrauterine hypoxia, or infections. |
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Authors:
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Klára Töro; Martha Hubay; Eva Keller |
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Publication Detail:
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Type: Journal Article Date: 2006-09-27 |
Journal Detail:
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Title: Forensic science international Volume: 170 ISSN: 1872-6283 ISO Abbreviation: Forensic Sci. Int. Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-07-04 Completed Date: 2007-10-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7902034 Medline TA: Forensic Sci Int Country: Ireland |
Other Details:
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Languages: eng Pagination: 15-9 Citation Subset: IM |
Affiliation:
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Department of Forensic Medicine, Semmelweis University, Ulloi út 93, Budapest 1091, Hungary. torok@igaz.sote.hu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Case-Control Studies Erythroblasts / pathology Forensic Pathology Hematopoiesis, Extramedullary* Humans Immunohistochemistry Infant Infant, Newborn Liver / pathology Sudden Infant Death / pathology* |
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