| Extramammary Paget disease: Immunohistochemistry is critical to distinguish potential mimickers. | |
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MedLine Citation:
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PMID: 23031371 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Extra-mammary Paget disease (EMPD) is a rare intra-epithelial carcinoma that is usually found on the apocrine-rich skin of the perineum. We report 2 cases in which EMPD was initially misdiagnosed on the initial punch biopsy as melanoma-in-situ and Bowen disease respectively. Reasons for the misdiagnoses included a rare pigmented axillary variant of EMPD in the first case and atypical bowenoid features on H&E in the second. The cases are described with a critical review of the histopathological findings, along with a review of the current literature. This highlights the necessity of a comprehensive immunohistochemical panel for the assessment of intra-epithelial pagetoid atypical cells. |
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Authors:
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Etienne Ce Wang; Yung Chien Kwah; Wee Ping Tan; Joyce Ss Lee; Suat Hoon Tan |
Publication Detail:
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Type: Journal Article Date: 2012-09-15 |
Journal Detail:
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Title: Dermatology online journal Volume: 18 ISSN: 1087-2108 ISO Abbreviation: Dermatol. Online J. Publication Date: 2012 |
Date Detail:
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Created Date: 2012-10-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610776 Medline TA: Dermatol Online J Country: United States |
Other Details:
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Languages: eng Pagination: 4 Citation Subset: IM |
Affiliation:
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National Skin Centre, Singapore. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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