Document Detail


Extraintestinal salmonellosis in a children's hospital.
MedLine Citation:
PMID:  9154541     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: An increase in the number of patients presenting with extraintestinal salmonellosis has occurred at our institution. The purpose of this study was to review the extraintestinal salmonellosis cases in our institution and to investigate the possible reasons for this increase. METHODS: A retrospective review of patients from 1985 through 1996 was carried out to identify patients with extraintestinal infections with Salmonella. Demographic data were gathered and statistical evaluations comparing differences among groups (1985 to 1989, 1989 to 1992, 1993 to 1996) was done using the G statistic, adjusted (maximum likelihood) chi square or the Fisher's exact test. RESULTS: Thirty-nine patients were identified with extraintestinal salmonellosis and although the number of cases had increased from 8 in 1985 to 1988 to 18 in 1989 to 1992 and 13 from 1993 to 1996, the percentage of cases that were extraintestinal were similar (3.3%, 6%, 4.9%; P > 0.1). Seventy-two percent of patients had underlying risk factors with the most common being age < 3 months (44%), sickle cell anemia (13%) and gastrointestinal surgery (10%). Fever and diarrhea were more common presenting symptoms in patients < 3 months of age than in older patients (P < 0.05). Salmonella typhimurium and Salmonella heidelberg were the most common serotypes isolated and an increasing trend of ampicillin resistance was noted from 0% in 1985 to 1988 to 39% from 1989 to 1992 and 23% from 1993 to 1996. CONCLUSIONS: The reasons for an increasing trend in extraintestinal cases of human salmonellosis at our institution were not identified. This illness continues to occur in infants and children with well-recognized risk factors.
Authors:
G E Schutze; S E Schutze; R S Kirby
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  16     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-07-25     Completed Date:  1997-07-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  482-5     Citation Subset:  IM    
Affiliation:
University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock 72202-3591, USA. gschutze@achasc.uams.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Distribution
Chi-Square Distribution
Confidence Intervals
Cross Infection / diagnosis,  drug therapy,  epidemiology*,  microbiology
Drug Resistance, Microbial
Female
Hospitals, Pediatric / statistics & numerical data*
Humans
Incidence
Infant
Infant, Newborn
Male
Retrospective Studies
Risk Factors
Salmonella / classification
Salmonella Infections / diagnosis,  drug therapy,  epidemiology*,  microbiology
Serotyping
Sex Distribution
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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