Document Detail

Extrahepatic portal hypertension due to congenital obstruction of the portal vein and associated gross hepatic lobulation.
MedLine Citation:
PMID:  477173     Owner:  NLM     Status:  MEDLINE    
A 10-233k old girl presented with splenomegaly and recurrent hematemesis from esophageal varices. Splenoportography revealed a dilated extrahepatic portion of the portal vein with nonvisualization of its intrahepatic tributaries. The child died following an episode of hematemesis and was found to have a dilated portal vein which ended blindly. In addition, there was abnormal lobulation of the inferior surface of the liver which was not cirrhotic. The portal vascular anomaly, which presumably was responsible for the portal hypertension, was probably due to failure of communication between the embryonic vitelline veins or to atresia of the portal vein secondary to pressure from the abnormal hepatic lobulation in utero. It would appear that congenital factors may be significant in the etiology and pathogenesis of some cases of extrahepatic portal hypertension in early life and recognition of such developmental anomalies is of importantance in management.
A O Johnson; A O Obisesan; A O Williams
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical pediatrics     Volume:  18     ISSN:  0009-9228     ISO Abbreviation:  Clin Pediatr (Phila)     Publication Date:  1979 Oct 
Date Detail:
Created Date:  1979-11-28     Completed Date:  1979-11-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372606     Medline TA:  Clin Pediatr (Phila)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  619-21     Citation Subset:  AIM; IM    
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MeSH Terms
Hypertension, Portal / diagnosis,  etiology*
Liver / abnormalities*
Portal Vein / abnormalities*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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