| Extragenic suppression of two ribosomal protein cistrons lying near the rif locus in Escherichia coli. | |
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MedLine Citation:
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PMID: 770447 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The experiments reported here involve temperature-sensitive mutations in two of five cistrons encoding 50S ribosomal proteins that lie near the rif locus in Escherichia coli. I selected spontaneous TS+ mutants able to grow at elevated temperatures in which the TS+ event takes place outside this tract of cistrons near rif. Six distinct classes of extragenic suppressors were found, five of which have been mapped. Two of these suppressors lie near 64 min, a region known to be rich in cistrons ribosomal proteins (Dennis and Nomura, 1975). The remaining three extragenic suppressors were located near 16.5, 47, and 86 min. |
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Authors:
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B Molholt |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of bacteriology Volume: 126 ISSN: 0021-9193 ISO Abbreviation: J. Bacteriol. Publication Date: 1976 May |
Date Detail:
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Created Date: 1976-07-06 Completed Date: 1976-07-06 Revised Date: 2010-09-02 |
Medline Journal Info:
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Nlm Unique ID: 2985120R Medline TA: J Bacteriol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 563-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bacterial Proteins
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biosynthesis* Chromosome Mapping Conjugation, Genetic Drug Resistance, Microbial Escherichia coli / drug effects, metabolism* Genes* Mutation Ribosomes / metabolism Rifampin / pharmacology Suppression, Genetic* Temperature Transduction, Genetic |
| Chemical | |
Reg. No./Substance:
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0/Bacterial Proteins; 13292-46-1/Rifampin |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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