Document Detail

Extractive L-lactic acid fermentation with immobilized Rhizopus oryzae in a three-phase fluidized bed.
MedLine Citation:
PMID:  9429778     Owner:  NLM     Status:  MEDLINE    
The Rhizopus oryzae was immobilized by the calcium alginate entrapment method. A three-phase fluidized-bed bioreactor was designed to perform the immobilized-cell L-lactic acid fermentation. A solvent extraction column was coupled with the bioreactor to remove L-lactic acid from the fermentation broth. The TRPO was selected as solvent and sulfonated kerosene as diluent. The results indicated that the pH value in the broth was regulated above pH 3.5 and the fermentation rate was as high as 11 g L-lactic acid per hour per liter of beads. A mathematical model was proposed to describe the concentration of L-lactic acid in the extractive fermentation.
Y Lu; J Lin; S Li; X Li; Y Shu; P Cen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chinese journal of biotechnology     Volume:  13     ISSN:  1042-749X     ISO Abbreviation:  Chin. J. Biotechnol.     Publication Date:  1997  
Date Detail:
Created Date:  1998-02-11     Completed Date:  1998-02-11     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  9100855     Medline TA:  Chin J Biotechnol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  169-76     Citation Subset:  IM    
Department of Chemical Engineering, Zhejiang University, Hangzhou, China.
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MeSH Terms
Lactic Acid*
Reg. No./Substance:
50-21-5/Lactic Acid

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