| Extracting key messages from systematic reviews. | |
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MedLine Citation:
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PMID: 19034207 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Systematic reviews have become a common method of synthesizing literature to examine the comparative effectiveness of medical interventions. Groups such as the Cochrane Collaboration and the U.S. Agency for Healthcare Research and Quality (AHRQ) conduct dozens of such reviews each year. However, these documents are often hundreds of pages long and the intended audiences, including medical providers and payers, may have difficulty interpreting the often technical terminology used in these reports. In this article, we describe the derivation of "key concepts" on the efficacy of antiepileptic drugs (AEDs) in the treatment of bipolar disorder from a pre- viously published systematic review of the use of AEDs (AED Review) for multiple indications, including mood disorders and chronic pain. With the aid of a multidisciplinary science panel, we derived the key concepts from the source report and subsequent updates of that report. Because we found that the key concepts were still quite technical, we subsequently derived four less technical "key messages" and revised these through multiple additional iterations. The concepts and messages were then tested with key informants and focus groups. At all stages of the process, we found that it was critical to maintain fidelity to the initial systematic review. The structured approach used in the derivation process described here proved to be very helpful in developing key messages and concepts. |
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Authors:
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Timothy S Carey; Cathy L Melvin; Leah M Ranney |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of psychiatric practice Volume: 14 Suppl 1 ISSN: 1538-1145 ISO Abbreviation: J Psychiatr Pract Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-11-26 Completed Date: 2009-02-10 Revised Date: 2009-03-10 |
Medline Journal Info:
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Nlm Unique ID: 100901141 Medline TA: J Psychiatr Pract Country: United States |
Other Details:
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Languages: eng Pagination: 28-34 Citation Subset: IM |
Affiliation:
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The Cecil G. Sheps Center for Health Services Research, The University of North Carolina at Chapel Hill, NC 27599-7590, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anticonvulsants
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therapeutic use* Bipolar Disorder / drug therapy* Evidence-Based Medicine / methods* Humans Information Dissemination* Review Literature as Topic* United States |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants |
| Comments/Corrections | |
Erratum In:
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J Psychiatr Pract. 2008 May;14(3):193 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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