Document Detail

Extracting key messages from systematic reviews.
MedLine Citation:
PMID:  19034207     Owner:  NLM     Status:  MEDLINE    
Systematic reviews have become a common method of synthesizing literature to examine the comparative effectiveness of medical interventions. Groups such as the Cochrane Collaboration and the U.S. Agency for Healthcare Research and Quality (AHRQ) conduct dozens of such reviews each year. However, these documents are often hundreds of pages long and the intended audiences, including medical providers and payers, may have difficulty interpreting the often technical terminology used in these reports. In this article, we describe the derivation of "key concepts" on the efficacy of antiepileptic drugs (AEDs) in the treatment of bipolar disorder from a pre- viously published systematic review of the use of AEDs (AED Review) for multiple indications, including mood disorders and chronic pain. With the aid of a multidisciplinary science panel, we derived the key concepts from the source report and subsequent updates of that report. Because we found that the key concepts were still quite technical, we subsequently derived four less technical "key messages" and revised these through multiple additional iterations. The concepts and messages were then tested with key informants and focus groups. At all stages of the process, we found that it was critical to maintain fidelity to the initial systematic review. The structured approach used in the derivation process described here proved to be very helpful in developing key messages and concepts.
Timothy S Carey; Cathy L Melvin; Leah M Ranney
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of psychiatric practice     Volume:  14 Suppl 1     ISSN:  1538-1145     ISO Abbreviation:  J Psychiatr Pract     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-11-26     Completed Date:  2009-02-10     Revised Date:  2009-03-10    
Medline Journal Info:
Nlm Unique ID:  100901141     Medline TA:  J Psychiatr Pract     Country:  United States    
Other Details:
Languages:  eng     Pagination:  28-34     Citation Subset:  IM    
The Cecil G. Sheps Center for Health Services Research, The University of North Carolina at Chapel Hill, NC 27599-7590, USA.
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MeSH Terms
Anticonvulsants / therapeutic use*
Bipolar Disorder / drug therapy*
Evidence-Based Medicine / methods*
Information Dissemination*
Review Literature as Topic*
United States
Reg. No./Substance:
Erratum In:
J Psychiatr Pract. 2008 May;14(3):193

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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