Document Detail

Extracorporeal shock wave lithotripsy is effective in treating single melamine-induced urolithiasis in infants and young children.
MedLine Citation:
PMID:  23201375     Owner:  NLM     Status:  Publisher    
PURPOSE: To evaluate the efficacy of extracorporeal shock wave lithotripsy (ESWL) in treating infant melamine-induced single urolithiasis. MATERIALS AND METHODS: Between March 2009 and July 2010, 189 infants and young children with single melamine-induced urolithiasis were referred to our center for treatment by ESWL. There were 17 patients with proximal ureteric calculi, 5 with mid-ureteric calculi, 26 with distal ureteric calculi and 141 with renal calculi. The stone size ranged from 3.8mm to 25mm (with a mean size of 9.79±3.83 mm). RESULTS: All the patients underwent ESWL using the same device with an energy ranging from 8 KV to 12 KV. The stone-free rate, clinical insignificant residual fragment rate and retreatment rate were 97.88%, 1.59% and 2.65%, respectively. One hundred and eighty (95.24%) patients required only one ESWL session and 5 (2.65%) patients required two sessions. The mean number of shocks delivered per session was 580.36±190.69 (ranging 65 to 950). ESWL failed to fragment stones in only one infant, who had a proximal ureteral stone. Totally 181 specimens were collected and were analyzed by infrared spectrum. The results showed that the main composition was uric acid and melamine. All the patients were followed for a mean period of 28 months (ranging 20-36 months). No severe complications, such as renal subcapsular hemorrhage, hypertension, kidney ruptured, or lung injury were observed. CONCLUSIONS: ESWL with low energy can effectively disintegrate melamine-induced calculi. It has become our preferred method for single melamine-induced urolithiasis in infants and young children.
Jianye Jia; Xiaowei Shen; Liya Wang; Tiejun Zhang; Maosheng Xu; Xiaoliang Fang; Guofeng Xu; Chen Qian; Yeming Wu; Hongquan Geng
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-27
Journal Detail:
Title:  The Journal of urology     Volume:  -     ISSN:  1527-3792     ISO Abbreviation:  J. Urol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-12-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.
Department of Pediatric Urology, Xinhua Hospital, Shanghai Jiao tong University School of Medicine, Shanghai, China; Children's Urolithiasis Treatment Center of Chinese Ministry of Health, Shanghai China.
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