Document Detail

Extracorporeal sensing techniques.
MedLine Citation:
PMID:  15876826     Owner:  NLM     Status:  MEDLINE    
Many physiologic variables have been measured in the extracorporeal circulation by experimental systems but only a few systems have reached technical maturity for everyday application. Variables relating to cardiovascular function, which today can be measured in the extracorporeal system, are pressure, temperature, and measures of blood composition such as hematocrit, hemoglobin, and total protein concentration. While the measurement of blood composition and temperature is well established, and while the use of extracorporeal pressure information awaits further analysis for robust application, recent interest focused on continuous measurement of plasma sodium concentration which is believed to be of major importance for optimal blood treatment. However, problems with a simple, reliable, and continuous measurement of plasma sodium for everyday use have not yet been resolved. As can be seen from the growing interest in isothermic or isonatremic treatment modes which turns away from constant and profiled treatment modes without feedback control, the treatment goal is now to provide stable conditions within the patient so as to minimize interference with intrinsic physiological control mechanisms. This, however, requires valid and reliable measurement of the specific patient variables of interest.
Daniel Schneditz
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Contributions to nephrology     Volume:  149     ISSN:  0302-5144     ISO Abbreviation:  Contrib Nephrol     Publication Date:  2005  
Date Detail:
Created Date:  2005-05-06     Completed Date:  2005-06-28     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7513582     Medline TA:  Contrib Nephrol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  35-41     Citation Subset:  IM    
Institute of Physiology, Medical University Graz, Graz, Austria.
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MeSH Terms
Blood Physiological Phenomena*
Cardiology / methods*
Cardiovascular Physiological Phenomena*
Extracorporeal Circulation*
Osmolar Concentration
Sodium / blood
Reg. No./Substance:

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