Document Detail


Extracorporeal perfusion of the whole human placenta--a new model.
MedLine Citation:
PMID:  6963967     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An extracorporeal dual perfusion system of the whole human placenta was developed using a technique of multiple blunt cannulations of the intervillous space. The system was evaluated according to various perfusion-dynamic, metabolic and morphological criteria. Angiographic and dye distribution studies showed 80 to 100 per cent perfusion of the placenta. The perfused organ consumed oxygen, utilized glucose and produced HCG. The flow rates and acid-base values were within acceptable limits. However, problems with high fetoplacental vascular resistance, tendency to metabolic acidosis and fetomaternal fluid transfer were encountered. Ultrastructural studies showed variations in the syncytiotrophoblast and the microvilli.
Authors:
D Maulik; S F Contractor; J Lippes; A Knight
Related Documents :
10404727 - Sensitivity of electrospray-tandem mass spectrometry using the phenylalanine/tyrosine-r...
14601277 - An easy method of mentally estimating the metabolic component of acid/base balance usin...
15088937 - Antimicrobial activities of n-(2-hydroxy-1-naphthalidene)-amino acid(glycine, alanine, ...
22227267 - Coffee polyphenol caffeic acid but not chlorogenic acid increases 5'amp-activated prote...
22653277 - A dual mechanism of action for skeletal muscle fat/cd36 during exercise.
7788717 - Sequence analysis of the aspergillus nidulans pectate lyase pela gene and evidence for ...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Placenta. Supplement     Volume:  3     ISSN:  0265-7023     ISO Abbreviation:  Placenta Suppl     Publication Date:  1981  
Date Detail:
Created Date:  1983-08-26     Completed Date:  1983-08-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8306308     Medline TA:  Placenta Suppl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  353-65     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acid-Base Equilibrium
Angiography
Female
Glucose / metabolism
Humans
Models, Biological*
Oxygen / blood
Oxygen Consumption
Perfusion / methods*
Placenta / blood supply*,  metabolism
Pregnancy
Chemical
Reg. No./Substance:
50-99-7/Glucose; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Acetylcholine in human term placenta: tissue levels in intact fragments after inhibition in vitro of...
Next Document:  Studies of antigenic components of the human syncytiotrophoblast membrane.