| Extracorporeal perfusion of the whole human placenta--a new model. | |
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MedLine Citation:
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PMID: 6963967 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An extracorporeal dual perfusion system of the whole human placenta was developed using a technique of multiple blunt cannulations of the intervillous space. The system was evaluated according to various perfusion-dynamic, metabolic and morphological criteria. Angiographic and dye distribution studies showed 80 to 100 per cent perfusion of the placenta. The perfused organ consumed oxygen, utilized glucose and produced HCG. The flow rates and acid-base values were within acceptable limits. However, problems with high fetoplacental vascular resistance, tendency to metabolic acidosis and fetomaternal fluid transfer were encountered. Ultrastructural studies showed variations in the syncytiotrophoblast and the microvilli. |
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Authors:
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D Maulik; S F Contractor; J Lippes; A Knight |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Placenta. Supplement Volume: 3 ISSN: 0265-7023 ISO Abbreviation: Placenta Suppl Publication Date: 1981 |
Date Detail:
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Created Date: 1983-08-26 Completed Date: 1983-08-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8306308 Medline TA: Placenta Suppl Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 353-65 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acid-Base Equilibrium Angiography Female Glucose / metabolism Humans Models, Biological* Oxygen / blood Oxygen Consumption Perfusion / methods* Placenta / blood supply*, metabolism Pregnancy |
| Chemical | |
Reg. No./Substance:
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50-99-7/Glucose; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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