Document Detail

Extracorporeal membrane oxygenation for transport of hypoxaemic patients with severe ARDS.
MedLine Citation:
PMID:  9135298     Owner:  NLM     Status:  MEDLINE    
Conventional inter-hospital transfer of patients with severe acute respiratory distress syndrome (ARDS) in need of extracorporeal membrane oxygenation (ECMO) may be risky and in severe hypoxaemic patients may be associated with cerebral hypoxia and death. Therefore, we began a phase 1 study to evaluate the feasibility, complications and outcome of inter-hospital transport of these patients using veno-venous ECMO. Eight patients with severe ARDS and a PaO2/FIO2 < 6.7 kPa at a PEEP > or = 10 cm H2O were placed on a mobile ECMO at the referring hospital. The 495 (SD 123) km inter-hospital transport via a special ground ambulance took 341 (151) min. After transfer, blood-gas tensions were improved in spite of less optimal ventilator settings, compared with data before the start of ECMO. No significant complications occurred. Six patients survived and were discharged from hospital; two patients died because of multiple organ failure. We conclude that initiation of ECMO in hypoxaemic patients before inter-hospital transfer is feasible and enables safe transport to an ECMO centre.
R Rossaint; D Pappert; H Gerlach; K Lewandowski; D Keh; K Falke
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Publication Detail:
Type:  Clinical Trial; Clinical Trial, Phase I; Journal Article    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  78     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1997 Mar 
Date Detail:
Created Date:  1997-05-15     Completed Date:  1997-05-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  241-6     Citation Subset:  IM    
Klinik für Anaesthesiologie und operative Intensivmedizin, Virchow-Klinikum der Medizinischen Fakultät der Humboldt-Universität zu Berlin, Germany.
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MeSH Terms
Ambulatory Care / methods
Anoxia / physiopathology,  therapy*
Extracorporeal Membrane Oxygenation*
Feasibility Studies
Middle Aged
Patient Transfer / methods*
Pulmonary Gas Exchange
Respiratory Distress Syndrome, Adult / physiopathology,  therapy*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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