| Extracorporeal membrane oxygenation support for intractable primary arrhythmias and complete congenital heart block in newborns and infants: Short-term and medium-term outcomes. | |
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MedLine Citation:
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PMID: 21516054 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVES:: To describe the experience with extracorporeal membrane oxygenation support for intractable primary arrhythmias in newborns and infants. DESIGN:: Retrospective study. SETTING:: A tertiary care pediatric hospital. PATIENTS:: Patients younger than 1 yr supported with extracorporeal membrane oxygenation for primary cardiac arrhythmias were identified from the institutional extracorporeal membrane oxygenation registry. INTERVENTIONS:: Extracorporeal membrane oxygenation support. MEASUREMENTS AND MAIN RESULTS:: Clinical characteristics and outcomes were investigated for patients with primary cardiac arrhythmia supported with extracorporeal membrane oxygenation. Outcomes investigated were time from initiation of extracorporeal membrane oxygenation support to arrhythmia control, duration of extracorporeal membrane oxygenation support, and results of interventions performed while supported with extracorporeal membrane oxygenation. We summarized the independent categorical and continuous variables using frequencies, percentages, and medians and ranges, respectively. Extracorporeal membrane oxygenation support was used in nine patients for rescue therapy for primary tachyarrhythmia and bradycardia. The primary arrhythmias were: focal atrial tachycardia (n = 2); reentrant supraventricular tachycardia (n = 3); junctional ectopic tachycardia (n = 2); and congenital complete atrioventricular block (n = 2) patients. Seven patients presented with severe hemodynamic compromise, with six patients requiring extracorporeal cardiopulmonary resuscitation. All patients required extracorporeal membrane oxygenation within 24 hrs of initial presentation. Balloon atrial septostomy was performed in three patients and ablation was performed in two patients. Sinus rhythm was achieved in all reentrant supraventricular tachycardia and rate control was established in both patients with focal atrial tachycardia and in one patient with junctional ectopic tachycardia while using extracorporeal membrane oxygenation support. All patients survived to hospital discharge, and median follow-up for the cohort was 5 yrs. There was one late death; all survivors had good overall and neurologic outcomes. CONCLUSIONS:: The requirement of extracorporeal membrane oxygenation support in newborns and infants with intractable arrhythmia is rare. Extracorporeal membrane oxygenation support does potentially carry morbidity; however, to prevent arrhythmia-related mortality, extracorporeal membrane oxygenation support and/or extracorporeal cardiopulmonary resuscitation should be considered in the management of hemodynamically unstable primary arrhythmias as an emergent lifesaving procedure. |
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Authors:
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Umesh Dyamenahalli; Volkan Tuzcu; Eudice Fontenot; John Papagiannis; Rdb Jaquiss; Adnan Bhutta; William R Morrow; Christopher C Erickson; Michiaki Imamura; Parthak Prodhan |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-21 |
Journal Detail:
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Title: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies Volume: - ISSN: 1529-7535 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100954653 Medline TA: Pediatr Crit Care Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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From the Department of Pediatrics (UD, VT, EF, AB, WRM, PP), Section of Cardiology, Department of Pediatrics (UD, AB, PP), Cardiac Critical Care, and Department of Surgery (MI), Pediatric and Congenital Cardiac Surgery, Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, AR; NMC/CUMC/Children's Hospital and Medical Center (CCE), Omaha, NE; Duke University School of Medicine (RJ), Durham, NC; Mitera Children's Hospital (JP), Athens, Greece. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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