Document Detail

Extracorporeal membrane oxygenation is superior to right ventricular assist device for acute right ventricular failure after heart transplantation.
MedLine Citation:
PMID:  15511449     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Acute right ventricular failure after heart transplantation is a life-threatening condition, and sometimes the use of mechanical circulatory support is inevitable. The aim of this retrospective study was to investigate the effectiveness of two different mechanical circulatory support systems for this indication. METHODS: From 1984 to 2003, 28 heart transplant recipients exhibited right ventricular failure resistant to drug therapy. Right ventricular assist device (n = 15) or extracorporeal membrane oxygenation (n = 13) was implanted to support the failing heart. RESULTS: Overall in-hospital survival was 43%. In the right ventricular assist device group, only 2 patients (13%) could be weaned from mechanical circulatory support compared with 10 patients (77%) in the extracorporeal membrane oxygenation group (p = 0.001). Retransplantation was necessary in 6 patients in the right ventricular assist device group and in 1 patient in the extracorporeal membrane oxygenation group (p = 0.049). There was no difference in patient survival between groups, but graft survival was significantly better in the extracorporeal membrane oxygenation group (p = 0.005). CONCLUSIONS: In view of these results, extracorporeal membrane oxygenation seems to be the better option as mechanical circulatory support for right ventricular failure in heart transplantation.
Shahrokh Taghavi; Andreas Zuckermann; Jan Ankersmit; Georg Wieselthaler; Angela Rajek; Günther Laufer; Ernst Wolner; Michael Grimm
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  78     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-10-29     Completed Date:  2005-02-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1644-9     Citation Subset:  AIM; IM    
Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria.
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MeSH Terms
Extracorporeal Membrane Oxygenation*
Heart Transplantation*
Heart-Assist Devices*
Life Tables
Middle Aged
Multiple Organ Failure / etiology,  mortality
Postoperative Complications / mortality,  therapy*
Postoperative Hemorrhage / epidemiology
Retrospective Studies
Sepsis / epidemiology
Survival Analysis
Treatment Outcome
Ventricular Dysfunction, Right / etiology,  mortality,  therapy*

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