Document Detail

Extracorporeal life support as ultimate strategy for refractory severe cardiogenic shock induced by Tako-tsubo cardiomyopathy: a new effective therapeutic option.
MedLine Citation:
PMID:  19681838     Owner:  NLM     Status:  MEDLINE    
We report a possible new therapeutic strategy, using extracorporeal cardiopulmonary support (ECLS), for severe refractory cardiogenic shock (SRCS) in a patient with Tako-tsubo cardiomyopathy (TC). TC is a syndrome characterized by left ventricular wall motion abnormalities, without coronary artery disease, mimicking the diagnosis of acute coronary syndrome. This ventricular dysfunction can be reversible; however, it can progress into refractory cardiogenic shock with limited therapeutic options available. For the first time in a Tako-tsubo patient with refractory cardiogenic shock, we used ECLS treatment in order to rest the heart, sustain circulation and end-organ perfusion, and promote potential ventricular recovery. ECLS might be the selected treatment for SRCS in patients with TC, and seems to be an effective and useful ultimate therapeutic strategy for preventing death.
Massimo Bonacchi; Serafina Valente; Guy Harmelin; Gian Franco Gensini; Guido Sani
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-07-22
Journal Detail:
Title:  Artificial organs     Volume:  33     ISSN:  1525-1594     ISO Abbreviation:  Artif Organs     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-23     Completed Date:  2010-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802778     Medline TA:  Artif Organs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  866-70     Citation Subset:  IM    
Cardiac Surgery, Medical and Surgical Critical Care Department, University of Florence, Viale Morgagni 85, Florence, Italy.
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MeSH Terms
Cardiovascular Agents / therapeutic use
Echocardiography, Transesophageal
Extracorporeal Circulation*
Intra-Aortic Balloon Pumping
Recovery of Function
Severity of Illness Index
Shock, Cardiogenic / diagnosis,  etiology,  physiopathology,  therapy*
Stress, Psychological / complications*,  physiopathology
Takotsubo Cardiomyopathy / diagnosis,  etiology,  physiopathology,  therapy*
Treatment Failure
Ventricular Function, Left
Reg. No./Substance:
0/Cardiovascular Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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