Document Detail


Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: the RELIEF trial.
MedLine Citation:
PMID:  23213075     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONCLUSION: At scheduled doses, a beneficial effect on survival of MARS therapy in patients with ACLF could not be demonstrated. However, MARS has an acceptable safety profile, has significant dialysis effect, and nonsignificantly improves severe HE.
Authors:
Rafael Bañares; Frederik Nevens; Fin Stolze Larsen; Rajiv Jalan; Agustín Albillos; Matthias Dollinger; Faouzi Saliba; Tilman Sauerbruch; Sebastian Klammt; Johann Ockenga; Albert Pares; Julia Wendon; Tanja Brünnler; Ludwig Kramer; Philippe Mathurin; Manuel de la Mata; Antonio Gasbarrini; Beat Müllhaupt; Alexander Wilmer; Wim Laleman; Martin Eefsen; Sambit Sen; Alexander Zipprich; Teresa Tenorio; Marco Pavesi; Hartmut H-J Schmidt; Steffen Mitzner; Roger Williams; Vicente Arroyo;
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Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2013-02-15
Journal Detail:
Title:  Hepatology (Baltimore, Md.)     Volume:  57     ISSN:  1527-3350     ISO Abbreviation:  Hepatology     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-03-04     Completed Date:  2013-04-23     Revised Date:  2013-11-19    
Medline Journal Info:
Nlm Unique ID:  8302946     Medline TA:  Hepatology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1153-62     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 American Association for the Study of Liver Diseases.
Affiliation:
Liver Unit, Hospital General Universitario Gregorio Marañón, IiSGM, Medical School, Universidad Complutense, Madrid, Spain. rbanares.hgugm@salud.madrid.org
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MeSH Terms
Descriptor/Qualifier:
Adult
End Stage Liver Disease / mortality,  therapy*
Female
Hospitalization / statistics & numerical data
Humans
Liver Cirrhosis / mortality,  therapy
Liver Failure, Acute / mortality,  therapy*
Logistic Models
Male
Middle Aged
Multiple Organ Failure / mortality,  therapy
Multivariate Analysis
Peritonitis / mortality,  therapy
Prospective Studies
Renal Dialysis / adverse effects,  methods
Serum Albumin / metabolism*
Sorption Detoxification / adverse effects,  methods*,  mortality
Treatment Outcome
Chemical
Reg. No./Substance:
0/Serum Albumin
Investigator
Investigator/Affiliation:
María-Vega Catalina / ; Maribel Durango / ; Rosario González-Alonso / ; Fernando Liaño / ; Cristina Martín / ; Beatriz Peñas / ; Pamela Leckie / ; Rajeshwar P Mookerjee / ; Lisa Cheshire / ; Silja Gläser / ; Beate Appenrodt / ; Felix Rockmann / ; Jürgen Schölmerich / ; Pieter Evenepoel / ; Greet Hermans / ; Philippe Meersseman / ; Joost Wauters / ; Philippe Ichaï / ; Didier Samuel / ; Magali Belnard / ; Juan Carlos Pozo / ; Jose Luis Montero / ; Angels Escorsell / ; Antoni Mas /
Comments/Corrections
Comment In:
Z Gastroenterol. 2013 Oct;51(10):1193-4   [PMID:  24122382 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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