| Extracellular matrix-derived peptides and myocardial repair. | |
| | |
MedLine Citation:
|
PMID: 21048428 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Repairing cardiac tissue remains one of the most challenging goals in tissue engineering. Here, we discuss ways whereby we sought to treat myocardial infarctions using extracellular-matrix derived peptides. Using an ischemia/reperfusion myocardial infarction rodent model, we targeted these extracellular matrix-derived peptides to the myocardial infarct site and were able to induce angiogenesis and alter the negative remodeling seen after an acute myocardial infarction. Our results indicate a potentially new strategy for repairing damaged tissue. |
| | |
Authors:
|
Shirley S Mihardja; Jiashing Yu; Randall J Lee |
Related Documents
:
|
18043998 - Plasma brain natriuretic peptide and systemic ventricular function in asymptomatic pati... 20811898 - Influence of acute and chronic myocardial loading conditions, function, structural chan... 12783068 - B-type natriuretic peptides. a diagnostic breakthrough in heart failure. 19157978 - Determinants of elevated nt-probnp levels in patients with hypertrophic cardiomyopathy:... 17041708 - Left ventricular outflow tract obstruction after bioprosthetic mitral valve replacement... 21299888 - Socioeconomic status and mortality after acute myocardial infarction: a study from iran. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2011-03-01 |
Journal Detail:
|
Title: Cell adhesion & migration Volume: 5 ISSN: 1933-6926 ISO Abbreviation: Cell Adh Migr Publication Date: 2011 Mar-Apr |
Date Detail:
|
Created Date: 2011-04-11 Completed Date: 2011-08-12 Revised Date: 2012-09-18 |
Medline Journal Info:
|
Nlm Unique ID: 101469464 Medline TA: Cell Adh Migr Country: United States |
Other Details:
|
Languages: eng Pagination: 111-3 Citation Subset: IM |
Affiliation:
|
Cardiovascular Research Institute, University of California-San Francisco, CA, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Angiogenesis Inducing Agents
/
administration & dosage,
therapeutic use* Animals Antibodies / metabolism Disease Models, Animal Extracellular Matrix / chemistry Extracellular Matrix Proteins / administration & dosage, chemistry, therapeutic use* Immunoconjugates / metabolism Myocardial Infarction / drug therapy*, physiopathology Myocardium / metabolism, pathology Peptides / administration & dosage, chemistry, therapeutic use* Rats Reperfusion Injury / chemically induced, drug therapy* Tissue Engineering / methods Ventricular Remodeling / drug effects |
| Chemical | |
Reg. No./Substance:
|
0/Angiogenesis Inducing Agents; 0/Antibodies; 0/Extracellular Matrix Proteins; 0/Immunoconjugates; 0/Peptides |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Epigenetic regulation of immune cell functions during post-septic immunosuppression.
Next Document: Statin therapy significantly reduces risk of ventricular tachyarrhythmias in patients with an implan...