Document Detail

Is Extracellular Volume Expansion of Peritoneal Dialysis Patients Associated with Greater Urine Output?
MedLine Citation:
PMID:  21829014     Owner:  NLM     Status:  Publisher    
Background and Objectives: Residual renal function (RRF) is important for peritoneal dialysis (PD) technique failure and patient survival. Reduction in extracellular water (ECW) has been reported to reduce urine output. We audited volume status and RRF to determine whether ECW was linked to urinary output. Methods: We retrospectively audited PD patients who had RRF and multiple frequency bioimpedance spectroscopy assessments. Results: 550 patients were studied. Urine output was lower in males (p = 0.021), non-Caucasoids (p = 0.04), those prescribed antihypertensives (p < 0.001), and greater glucose dialysate usage (p < 0.001). Urine output was negatively associated with dialysis vintage (F = 40.7, β -0.627, p < 0.001), and ECW (F = 33.7, β -0.177, p < 0.001) and positively associated with intracellular volume (F = 34.6, β 0.11, p < 0.001). Conclusions: RRF is important for successful PD, and ECW volume expansion may lead to better preservation of RRF in PD patients compared to haemodialysis. However, in our retrospective cross-sectional study, ECW expansion was associated with reduced urine output.
Andrew Davenport; Rabya Hussain Sayed; Stanley Fan
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-09
Journal Detail:
Title:  Blood purification     Volume:  32     ISSN:  1421-9735     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8402040     Medline TA:  Blood Purif     Country:  -    
Other Details:
Languages:  ENG     Pagination:  226-231     Citation Subset:  -    
Copyright Information:
Copyright © 2011 S. Karger AG, Basel.
UCL Center for Nephrology, University College London Medical School, Royal Free Campus, London, UK.
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